Our experience of liver Epithelioid Hemangioendothelioma: From a misdiagnosis to liver transplantation with long term follow-up

Antonio Giuliani, Bruno Amato, Giuseppina Marino Marsilia, Domenico Tafuri, Antonio Ceriello, Walter Santaniello, Loredana Sodano, Aldo Rocca

Research output: Contribution to journalArticle

Abstract

Malignant Hepatic Epithelioid hemangioendothelioma (HEHE) is an uncommon vascular tumor of intermediate malignant potential. HEHE is a rare tumor and it is difficult to diagnose for surgeons, hepatologists, radiologists and pathologists. So, misdiagnosis with a delay of the treatment is not uncommon. We describe a case of a young woman with a diagnosis of HEHE made 6 years after the first evidence of liver mass with a very long term follow-up after surgical treatment. She had two diagnoses of Hepatocellurar carcinoma (HCC) and a diagnosis of Cholangiocarcinoma after three different fine needle biopsies. After clinical observation, a new laparoscopic core biopsy was performed. In a first time approach, considering clinical and radiological patterns, a diagnosis of Budd-Chiari Syndrome was finally made. For that the patient underwent an orthotopicliver transplantation (OLTx). The surgical sample histological analysis allowed a definitive diagnosis of HEHE. At last, at follow up 7 years after three OLTx the patient is still alive and in good health with no evidence of recurrence.

Original languageEnglish
Pages (from-to)508-512
Number of pages5
JournalOpen Medicine (Poland)
Volume10
Issue number1
DOIs
Publication statusPublished - Jan 1 2015

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Keywords

  • Hepatichemangioendothelioma
  • laparoscopic liver surgery
  • liver transplantation

ASJC Scopus subject areas

  • Medicine(all)

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