Outcome measures in MMN revisited: Further improvement needed

Mariëlle H J Pruppers, Thomas H P Draak, Els K. Vanhoutte, W. Ludo Van Der Pol, Kenneth C. Gorson, Jean Marc Léger, Eduardo Nobile-Orazio, Richard A. Lewis, Leonard H. Van Den Berg, Catharina G. Faber, Ingemar S J Merkies

Research output: Contribution to journalArticlepeer-review


The objectives of this study were to provide an overview of the outcome measures (OMs) applied in clinical trials in multifocal motor neuropathy (MMN) and to determine the responsiveness of a core set of selected OMs as part of the peripheral neuropathy outcome measures standardization (PeriNomS) study. The following OMs were serially applied in 26 patients with newly diagnosed or relapsing MMN, receiving intravenous immunoglobulin (assessments: T0/T3/T12 months): 14 muscle pairs MRC (Medical Research Council) scale, the Neuropathy Impairment Scale motor-subset, a self-evaluation scale, grip strength, and MMN-RODS

Original languageEnglish
Pages (from-to)306-318
Number of pages13
JournalJournal of the Peripheral Nervous System
Issue number3
Publication statusPublished - Sep 1 2015


  • MMN
  • outcome measure

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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