TY - JOUR
T1 - Outcome measures in peripheral neuropathies
T2 - Requirements through statements
AU - Merkies, Ingemar S J
AU - Lauria, Giuseppe
AU - Faber, Catharina G.
PY - 2012/10
Y1 - 2012/10
N2 - Purpose of Review: The aim of this review is to inform and educate clinicians through statements about the most important clinimetric requirements for outcome measures in peripheral neuropathies. Recent Findings: The basic needs of an outcome measure (simple, valid, reliable, and responsive) are generally well known by physicians. However, techniques such as the Rasch methodology offer modern additional requirements, particularly in the development of interval-based outcome measures. Summary: Peripheral neuropathies are chronic disorders that generally cause deficits at the body level (impairments, e.g. weakness and sensory deficit) and may lead to problems in daily life and social functioning with a reduction in quality-of-life expectations. Fundamental steps should be taken in the design of clinical studies in peripheral neuropathies to ameliorate these deficits, of which the choice of a proper outcome measure representing the level of interest is considered a crucial one. However, choosing a proper outcome is not only dependent on the proposed research purpose, but perhaps more importantly, on the fulfilment of the clinimetric needs by the scale of interest. All outcome measures should be rigorously examined to determine their scientific soundness before being generally used. Respecting the basic needs of an outcome measure like being simple, valid, reliable, and responsive, this review will highlight through statements the modern scientific essentials in the design and evaluation of an outcome measure. The Rasch method as a modern vehicle will also be addressed, accentuating the need to shift towards a more modern clinimetric era. The presented findings could be applied to all forms of peripheral neuropathies.
AB - Purpose of Review: The aim of this review is to inform and educate clinicians through statements about the most important clinimetric requirements for outcome measures in peripheral neuropathies. Recent Findings: The basic needs of an outcome measure (simple, valid, reliable, and responsive) are generally well known by physicians. However, techniques such as the Rasch methodology offer modern additional requirements, particularly in the development of interval-based outcome measures. Summary: Peripheral neuropathies are chronic disorders that generally cause deficits at the body level (impairments, e.g. weakness and sensory deficit) and may lead to problems in daily life and social functioning with a reduction in quality-of-life expectations. Fundamental steps should be taken in the design of clinical studies in peripheral neuropathies to ameliorate these deficits, of which the choice of a proper outcome measure representing the level of interest is considered a crucial one. However, choosing a proper outcome is not only dependent on the proposed research purpose, but perhaps more importantly, on the fulfilment of the clinimetric needs by the scale of interest. All outcome measures should be rigorously examined to determine their scientific soundness before being generally used. Respecting the basic needs of an outcome measure like being simple, valid, reliable, and responsive, this review will highlight through statements the modern scientific essentials in the design and evaluation of an outcome measure. The Rasch method as a modern vehicle will also be addressed, accentuating the need to shift towards a more modern clinimetric era. The presented findings could be applied to all forms of peripheral neuropathies.
KW - clinimetrics
KW - MCID
KW - outcome measures
KW - peripheral neuropathies
KW - Rasch analysis
UR - http://www.scopus.com/inward/record.url?scp=84866341132&partnerID=8YFLogxK
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U2 - 10.1097/WCO.0b013e328357f30f
DO - 10.1097/WCO.0b013e328357f30f
M3 - Article
C2 - 22941264
AN - SCOPUS:84866341132
VL - 25
SP - 556
EP - 563
JO - Current Opinion in Neurology
JF - Current Opinion in Neurology
SN - 1350-7540
IS - 5
ER -