Twelve children born to hepatitis C virus antibody GBV-C/HGV RNA positive mothers who acquired GBV-C/HGV infection by the vertical or perinatal route were studied. Most (91%) were persistently GBV-C/HGV RNA positive up to 12 months of age. Four out of six cases who acquired GBV- C/HGV alone had normal alanine amino transferase activities. Long lasting evidence of hepatocellular injury was detected only in children with GBV- C/HGV and hepatitis C virus and HIV coinfection.
|Journal||Archives of Disease in Childhood: Fetal and Neonatal Edition|
|Publication status||Published - 1999|
- Hepatitis virus infection
- Mother to infant transmission
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health