Outcome of Nonpersonalized Human Papillomavirus Vaccinations During Postconization Follow-up: A Report of Two Cases

Luca Giannella, Kabala Mfuta, Cristina Fodero, Sonia Prandi

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: The human papillomavirus (HPV) vaccine was conceived to prevent new HPV infections among uninfected young women. From the initial intentions, its use has been extended to older women and also tested as a therapeutic tool. We report two HPV vaccination outcomes during postconization follow-up.

CASES: Two young women, with different clinical histories, were subjected to HPV vaccine after a loop electrosurgical excision procedure for high-grade cervical intraepithelial neoplasia (CIN) and persisting low-grade CIN. During follow-up both women experienced a worsening of cervical lesions, which resulted in invasive cervical cancer and severe dysplasia, respectively.

CONCLUSION: Limited to our experience, a nonpersonalized HPV vaccine administration during postconization follow-up was expensive and unnecessary.

Original languageEnglish
Pages (from-to)455-457
Number of pages3
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume60
Issue number9-10
Publication statusPublished - Sep 1 2015

ASJC Scopus subject areas

  • Medicine(all)

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