TY - JOUR
T1 - Outcome of patients treated by cardiac resynchronization therapy using a quadripolar left ventricular lead
AU - Bencardino, Gianluigi
AU - Di Monaco, Antonio
AU - Russo, Eleonora
AU - Colizzi, Cristian
AU - Perna, Francesco
AU - Pelargonio, Gemma
AU - Narducci, Maria Lucia
AU - Gabrielli, Francesca Augusta
AU - Lanza, Gaetano Antonio
AU - Rebuzzi, Antonio Giuseppe
AU - Crea, Filippo
PY - 2016/2/25
Y1 - 2016/2/25
N2 - Background: Not all heart failure (HF) patients benefit from cardiac resynchronization therapy (CRT). We assessed whether choosing the site of left ventricular (LV) pacing by a quadripolar lead may improve response to CRT. Methods and Results: We prospectively randomized 23 patients with HF (67±11 years; 21 males) to CRT with a quadripolar LV lead (group 1, with the LV pacing site chosen on the basis of QRS shortening using simultaneous biventricular pacing), and 20 patients (71±6 years; 16 males) to a bipolar LV lead (group 2, with devices programmed with a conventional tip-to-ring configuration). New York Heart Association (NYHA) class and LV ejection fraction (EF) by 2D echocardiography were assessed at baseline and after 3 months. The baseline EF was not different between the 2 groups (25±6% group 1 vs. 27±3% group 2; P=0.22), but after 3 months EF was higher in group 1 (35±13% group 1 vs. 31±4% group 2; P
AB - Background: Not all heart failure (HF) patients benefit from cardiac resynchronization therapy (CRT). We assessed whether choosing the site of left ventricular (LV) pacing by a quadripolar lead may improve response to CRT. Methods and Results: We prospectively randomized 23 patients with HF (67±11 years; 21 males) to CRT with a quadripolar LV lead (group 1, with the LV pacing site chosen on the basis of QRS shortening using simultaneous biventricular pacing), and 20 patients (71±6 years; 16 males) to a bipolar LV lead (group 2, with devices programmed with a conventional tip-to-ring configuration). New York Heart Association (NYHA) class and LV ejection fraction (EF) by 2D echocardiography were assessed at baseline and after 3 months. The baseline EF was not different between the 2 groups (25±6% group 1 vs. 27±3% group 2; P=0.22), but after 3 months EF was higher in group 1 (35±13% group 1 vs. 31±4% group 2; P
KW - Cardiac resynchronization therapy
KW - Heart failure
KW - Mortality
KW - Multipolar pacing
KW - Quadripolar lead
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U2 - 10.1253/circj.CJ-15-0932
DO - 10.1253/circj.CJ-15-0932
M3 - Article
AN - SCOPUS:84959020529
VL - 80
SP - 613
EP - 618
JO - Circulation Journal
JF - Circulation Journal
SN - 1346-9843
IS - 3
ER -