TY - JOUR
T1 - Outcomes of noncardiac, nonobstetric surgery in patients with PAH
T2 - An international prospective survey
AU - Meyer, Stephanie
AU - McLaughlin, Vallerie V.
AU - Seyfarth, Hans Juergen
AU - Bull, Todd M.
AU - Vizza, Carmine D.
AU - Gomberg-Maitlande, Mardi
AU - Preston, Ioana R.
AU - Barberà, Joan A.
AU - Hassoun, Paul M.
AU - Halank, Michael
AU - Jaïs, Xavier
AU - Nickel, Nils
AU - Hoeper, Marius M.
AU - Humbert, Marc
PY - 2013/6/1
Y1 - 2013/6/1
N2 - We conducted an international, prospective, 3-year questionnaire-based survey among 11 pulmonary hypertension centres to assemble data from patients with pulmonary arterial hypertension (PAH) undergoing noncardiac and nonobstetric surgery. Data were collected between July 2007 and June 2010 from 114 patients with PAH (70% female, mean age 57 years) who underwent major surgery. At the time of surgery, 43% were in functional class III/IV. 82% of the interventions were performed under general anaesthesia and 18% under spinal anaesthesia. Major complications occurred in seven (6.1%) of the patients, of whom four died, resulting in an overall perioperative mortality rate of 3.5%. The mortality rate was 15% (two out of 13) in emergency procedures, compared with 2% (two out of 101) in nonemergency procedures (p=0.01). Risk factors for major complications were an elevated right atrial pressure (OR 1.1, 95% CI 1.0-1.3; p=0.01), a 6-min walking distance
AB - We conducted an international, prospective, 3-year questionnaire-based survey among 11 pulmonary hypertension centres to assemble data from patients with pulmonary arterial hypertension (PAH) undergoing noncardiac and nonobstetric surgery. Data were collected between July 2007 and June 2010 from 114 patients with PAH (70% female, mean age 57 years) who underwent major surgery. At the time of surgery, 43% were in functional class III/IV. 82% of the interventions were performed under general anaesthesia and 18% under spinal anaesthesia. Major complications occurred in seven (6.1%) of the patients, of whom four died, resulting in an overall perioperative mortality rate of 3.5%. The mortality rate was 15% (two out of 13) in emergency procedures, compared with 2% (two out of 101) in nonemergency procedures (p=0.01). Risk factors for major complications were an elevated right atrial pressure (OR 1.1, 95% CI 1.0-1.3; p=0.01), a 6-min walking distance
KW - Anaesthesia
KW - Hypertension
KW - Pulmonary
KW - Surgery
KW - Survival
UR - http://www.scopus.com/inward/record.url?scp=84878772028&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84878772028&partnerID=8YFLogxK
U2 - 10.1183/09031936.00089212
DO - 10.1183/09031936.00089212
M3 - Article
C2 - 23143546
AN - SCOPUS:84878772028
VL - 41
SP - 1302
EP - 1307
JO - European Journal of Respiratory Diseases
JF - European Journal of Respiratory Diseases
SN - 0903-1936
IS - 6
ER -