Outcomes of patients with breast cancer who present with ipsilateral supraclavicular or internal mammary lymph node metastases

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Background The prognostic implications of internal mammary (IM) and supraclavicular (SC) node involvement in locally advanced breast cancer is still unclear. Patients and Methods We evaluated 107 patients with IM (n = 65) or SC (n = 42) node involvement who underwent operation at the European Institute of Oncology between 1997 and 2009 to assess their prognostic features. We subsequently analyzed matched cohorts, using the 107 patients as cases and another group of patients as a control cohort, to evaluate prognostic differences between patients with and those without IM or SC node involvement. Results Five-year disease-free survival (DFS) was 84% in IM vs. 38.8% in SC node involvement (P

Original languageEnglish
Pages (from-to)53-60
Number of pages8
JournalClinical Breast Cancer
Issue number1
Publication statusPublished - Feb 2014



  • Breast cancer
  • Internal mammary chain
  • Supraclavicular lymph nodes

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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