Abstract
Patients with Hodgkin lymphomas progressing after autologous stem cell transplantation (SCT) have a very poor outcome. Our retrospective analysis confirms that reduced-intensity conditioning allogeneic SCT may be an effective salvage strategy for patients who relapse after an autologous SCT and that outcomes are similar for both sibling and matched-unrelated donor transplants. Patients with active disease at transplantation have poor outcomes.
| Original language | English |
|---|---|
| Pages (from-to) | 35-40 |
| Number of pages | 6 |
| Journal | Clinical Lymphoma, Myeloma and Leukemia |
| Volume | 19 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1 2019 |
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Keywords
- Brentuximab vedotin
- Chemorefractory
- Graft-versus-malignancy
- Prognosis
- Refractory/relapsed HL after autologous SCT
ASJC Scopus subject areas
- Hematology
- Oncology
- Cancer Research
Cite this
Outcomes of Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplantation for Hodgkin Lymphomas : A Retrospective Multicenter Experience by the Rete Ematologica Pugliese (REP). / Gaudio, Francesco; Mazza, Patrizio; Carella, Angelo Michele; Mele, Anna; Palazzo, Giulia; Pisapia, Giovanni; Carluccio, Paola; Pastore, Domenico; Cascavilla, Nicola; Specchia, Giorgina; Pavone, Vincenzo.
In: Clinical Lymphoma, Myeloma and Leukemia, Vol. 19, No. 1, 01.01.2019, p. 35-40.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Outcomes of Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplantation for Hodgkin Lymphomas
T2 - A Retrospective Multicenter Experience by the Rete Ematologica Pugliese (REP)
AU - Gaudio, Francesco
AU - Mazza, Patrizio
AU - Carella, Angelo Michele
AU - Mele, Anna
AU - Palazzo, Giulia
AU - Pisapia, Giovanni
AU - Carluccio, Paola
AU - Pastore, Domenico
AU - Cascavilla, Nicola
AU - Specchia, Giorgina
AU - Pavone, Vincenzo
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Patients with Hodgkin lymphomas progressing after autologous stem cell transplantation (SCT) have a very poor outcome. Our retrospective analysis confirms that reduced-intensity conditioning allogeneic SCT may be an effective salvage strategy for patients who relapse after an autologous SCT and that outcomes are similar for both sibling and matched-unrelated donor transplants. Patients with active disease at transplantation have poor outcomes.
AB - Patients with Hodgkin lymphomas progressing after autologous stem cell transplantation (SCT) have a very poor outcome. Our retrospective analysis confirms that reduced-intensity conditioning allogeneic SCT may be an effective salvage strategy for patients who relapse after an autologous SCT and that outcomes are similar for both sibling and matched-unrelated donor transplants. Patients with active disease at transplantation have poor outcomes.
KW - Brentuximab vedotin
KW - Chemorefractory
KW - Graft-versus-malignancy
KW - Prognosis
KW - Refractory/relapsed HL after autologous SCT
UR - http://www.scopus.com/inward/record.url?scp=85054175645&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85054175645&partnerID=8YFLogxK
U2 - 10.1016/j.clml.2018.08.012
DO - 10.1016/j.clml.2018.08.012
M3 - Article
C2 - 30293754
AN - SCOPUS:85054175645
VL - 19
SP - 35
EP - 40
JO - Clinical Lymphoma, Myeloma and Leukemia
JF - Clinical Lymphoma, Myeloma and Leukemia
SN - 2152-2669
IS - 1
ER -