Outcomes of Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplantation for Hodgkin Lymphomas: A Retrospective Multicenter Experience by the Rete Ematologica Pugliese (REP)

Francesco Gaudio, Patrizio Mazza, Angelo Michele Carella, Anna Mele, Giulia Palazzo, Giovanni Pisapia, Paola Carluccio, Domenico Pastore, Nicola Cascavilla, Giorgina Specchia, Vincenzo Pavone

Research output: Contribution to journalArticle

Abstract

Patients with Hodgkin lymphomas progressing after autologous stem cell transplantation (SCT) have a very poor outcome. Our retrospective analysis confirms that reduced-intensity conditioning allogeneic SCT may be an effective salvage strategy for patients who relapse after an autologous SCT and that outcomes are similar for both sibling and matched-unrelated donor transplants. Patients with active disease at transplantation have poor outcomes.

Original languageEnglish
Pages (from-to)35-40
Number of pages6
JournalClinical Lymphoma, Myeloma and Leukemia
Volume19
Issue number1
DOIs
Publication statusPublished - Jan 1 2019

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Hematopoietic Stem Cell Transplantation
Stem Cell Transplantation
Hodgkin Disease
Unrelated Donors
Siblings
Transplantation
Transplants
Recurrence
Conditioning (Psychology)

Keywords

  • Brentuximab vedotin
  • Chemorefractory
  • Graft-versus-malignancy
  • Prognosis
  • Refractory/relapsed HL after autologous SCT

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

Cite this

Outcomes of Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplantation for Hodgkin Lymphomas : A Retrospective Multicenter Experience by the Rete Ematologica Pugliese (REP). / Gaudio, Francesco; Mazza, Patrizio; Carella, Angelo Michele; Mele, Anna; Palazzo, Giulia; Pisapia, Giovanni; Carluccio, Paola; Pastore, Domenico; Cascavilla, Nicola; Specchia, Giorgina; Pavone, Vincenzo.

In: Clinical Lymphoma, Myeloma and Leukemia, Vol. 19, No. 1, 01.01.2019, p. 35-40.

Research output: Contribution to journalArticle

Gaudio, Francesco ; Mazza, Patrizio ; Carella, Angelo Michele ; Mele, Anna ; Palazzo, Giulia ; Pisapia, Giovanni ; Carluccio, Paola ; Pastore, Domenico ; Cascavilla, Nicola ; Specchia, Giorgina ; Pavone, Vincenzo. / Outcomes of Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplantation for Hodgkin Lymphomas : A Retrospective Multicenter Experience by the Rete Ematologica Pugliese (REP). In: Clinical Lymphoma, Myeloma and Leukemia. 2019 ; Vol. 19, No. 1. pp. 35-40.
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