Outer retinal layer changes after dexamethasone implant for central retinal vein occlusion

M Battaglia Parodi, P Iacono, Matteo Scaramuzzi, F Bandello

Research output: Contribution to journalArticlepeer-review


PURPOSE:: To analyze the outer retinal layer changes on spectral-domain optical coherence tomography after dexamethasone implant for the treatment of macular edema secondary to central retinal vein occlusions (CRVO). METHODS:: Thirty patients affected by macular edema related to CRVO (8 patients less than 50 years of age with nonischemic CRVO [50-niCRVO], and 10 patients with ischemic CRVO [iCRVO]) were included in a prospective study. After a comprehensive ophthalmologic examination, including best-corrected visual acuity, fluorescein angiography, and spectral-domain optical coherence tomography, each patient received a first implant. Further retreatments were performed on the basis of macular edema detection from the fourth month. Main outcome measure was the change in outer retinal layers at the 12-month examination. RESULTS:: The retinal layers of interest (external limiting membrane; ellipsoid zone; and retinal pigment epithelium) were classified as absent, disrupted, or present. The best baseline optical coherence tomography profile was found in
Original languageEnglish
Pages (from-to)1888-1895
Number of pages8
Issue number10
Publication statusPublished - 2017


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