Ovarian endometriomas and oocyte quality: Insights from in vitro fertilization cycles

Research output: Contribution to journalArticle

Abstract

Objective To evaluate whether the presence of endometriomas affects ovarian function. Design Prospective cohort study. Setting Infertility unit of an academic setting. Patient(s) Twenty-nine women undergoing an IVF cycle. Intervention(s) Prospective evaluation of women with unoperated unilateral endometriomas undergoing IVF. The affected and contralateral intact gonads were compared in terms of responsiveness and oocyte quality. Main Outcome Measure(s) Oocyte developmental competence. Results Ovarian responsiveness and oocyte quality did not significantly differ between the affected and intact gonads. The number of codominant follicles, the number of oocytes retrieved, and the number of suitable oocytes in affected and intact gonads were 3.7 ± 2.4 and 4.1 ± 1.7, 4.2 ± 3.1 and 4.7 ± 2.5, and 3.1 ± 2.6 and 3.5 ± 2.3, respectively. The number of viable embryos and the number of high-quality embryos were 1.8 ± 2.1 and 1.8 ± 1.4 and 1.0 ± 1.7 and 0.8 ± 0.7, respectively. The fertilization rate in the affected and intact gonads was 64% and 64%, respectively. The cleavage rate was 58% and 51%, respectively. The rate of high-quality embryos was 31% and 21%, respectively. Conclusion(s) In women undergoing IVF, the presence of ovarian endometriomas does not affect oocyte developmental competence.

Original languageEnglish
JournalFertility and Sterility
Volume101
Issue number4
DOIs
Publication statusPublished - 2014

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Endometriosis
Fertilization in Vitro
Oocytes
Gonads
Embryonic Structures
Mental Competency
Fertilization
Infertility
Cohort Studies
Outcome Assessment (Health Care)
Prospective Studies

Keywords

  • Endometrioma
  • IVF
  • oocyte

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

Cite this

@article{528fac113e8743989503549bf821a48e,
title = "Ovarian endometriomas and oocyte quality: Insights from in vitro fertilization cycles",
abstract = "Objective To evaluate whether the presence of endometriomas affects ovarian function. Design Prospective cohort study. Setting Infertility unit of an academic setting. Patient(s) Twenty-nine women undergoing an IVF cycle. Intervention(s) Prospective evaluation of women with unoperated unilateral endometriomas undergoing IVF. The affected and contralateral intact gonads were compared in terms of responsiveness and oocyte quality. Main Outcome Measure(s) Oocyte developmental competence. Results Ovarian responsiveness and oocyte quality did not significantly differ between the affected and intact gonads. The number of codominant follicles, the number of oocytes retrieved, and the number of suitable oocytes in affected and intact gonads were 3.7 ± 2.4 and 4.1 ± 1.7, 4.2 ± 3.1 and 4.7 ± 2.5, and 3.1 ± 2.6 and 3.5 ± 2.3, respectively. The number of viable embryos and the number of high-quality embryos were 1.8 ± 2.1 and 1.8 ± 1.4 and 1.0 ± 1.7 and 0.8 ± 0.7, respectively. The fertilization rate in the affected and intact gonads was 64{\%} and 64{\%}, respectively. The cleavage rate was 58{\%} and 51{\%}, respectively. The rate of high-quality embryos was 31{\%} and 21{\%}, respectively. Conclusion(s) In women undergoing IVF, the presence of ovarian endometriomas does not affect oocyte developmental competence.",
keywords = "Endometrioma, IVF, oocyte",
author = "Francesca Filippi and Laura Benaglia and Alessio Paffoni and Liliana Restelli and Paolo Vercellini and Edgardo Somigliana and Luigi Fedele",
year = "2014",
doi = "10.1016/j.fertnstert.2014.01.008",
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journal = "Fertility and Sterility",
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T1 - Ovarian endometriomas and oocyte quality

T2 - Insights from in vitro fertilization cycles

AU - Filippi, Francesca

AU - Benaglia, Laura

AU - Paffoni, Alessio

AU - Restelli, Liliana

AU - Vercellini, Paolo

AU - Somigliana, Edgardo

AU - Fedele, Luigi

PY - 2014

Y1 - 2014

N2 - Objective To evaluate whether the presence of endometriomas affects ovarian function. Design Prospective cohort study. Setting Infertility unit of an academic setting. Patient(s) Twenty-nine women undergoing an IVF cycle. Intervention(s) Prospective evaluation of women with unoperated unilateral endometriomas undergoing IVF. The affected and contralateral intact gonads were compared in terms of responsiveness and oocyte quality. Main Outcome Measure(s) Oocyte developmental competence. Results Ovarian responsiveness and oocyte quality did not significantly differ between the affected and intact gonads. The number of codominant follicles, the number of oocytes retrieved, and the number of suitable oocytes in affected and intact gonads were 3.7 ± 2.4 and 4.1 ± 1.7, 4.2 ± 3.1 and 4.7 ± 2.5, and 3.1 ± 2.6 and 3.5 ± 2.3, respectively. The number of viable embryos and the number of high-quality embryos were 1.8 ± 2.1 and 1.8 ± 1.4 and 1.0 ± 1.7 and 0.8 ± 0.7, respectively. The fertilization rate in the affected and intact gonads was 64% and 64%, respectively. The cleavage rate was 58% and 51%, respectively. The rate of high-quality embryos was 31% and 21%, respectively. Conclusion(s) In women undergoing IVF, the presence of ovarian endometriomas does not affect oocyte developmental competence.

AB - Objective To evaluate whether the presence of endometriomas affects ovarian function. Design Prospective cohort study. Setting Infertility unit of an academic setting. Patient(s) Twenty-nine women undergoing an IVF cycle. Intervention(s) Prospective evaluation of women with unoperated unilateral endometriomas undergoing IVF. The affected and contralateral intact gonads were compared in terms of responsiveness and oocyte quality. Main Outcome Measure(s) Oocyte developmental competence. Results Ovarian responsiveness and oocyte quality did not significantly differ between the affected and intact gonads. The number of codominant follicles, the number of oocytes retrieved, and the number of suitable oocytes in affected and intact gonads were 3.7 ± 2.4 and 4.1 ± 1.7, 4.2 ± 3.1 and 4.7 ± 2.5, and 3.1 ± 2.6 and 3.5 ± 2.3, respectively. The number of viable embryos and the number of high-quality embryos were 1.8 ± 2.1 and 1.8 ± 1.4 and 1.0 ± 1.7 and 0.8 ± 0.7, respectively. The fertilization rate in the affected and intact gonads was 64% and 64%, respectively. The cleavage rate was 58% and 51%, respectively. The rate of high-quality embryos was 31% and 21%, respectively. Conclusion(s) In women undergoing IVF, the presence of ovarian endometriomas does not affect oocyte developmental competence.

KW - Endometrioma

KW - IVF

KW - oocyte

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