Ovarian germ cell cancer

Clinicopathologic analysis and outcome of 31 cases

S. Kusamura, L. C. Teixeira, M. A. Dos Santos, L. A L De Ângelo Andrade, J. C C Torres, A. Sagarra, M. Deraco, S. F M Derchain

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Aims: The aim of the study was to evaluate some clinicopathologic characteristics and the outcome of patients with ovarian germ cell cancer (OGCC) treated with cisplatin-based chemotherapy. Methods: It was a clinical retrospective study. The clinical charts of 31 patients with OGCC assisted at the Department of Obstetrics and Gynecology of the State University of Campinas, Brazil, from January 1986 to June 1997 were reviewed. Results: Ten patients had dysgerminoma and 21 patients nondysgerminomatous tumors. Women with dysgerminoma and nondysgerminomatous tumors did not present differences regarding surgical staging, age, ascites or residual tumor after the initial surgery. Frozen section, performed in 16 patients, showed some discrepancy with paraffin histology diagnosis in 8 patients. Platinum-based chemotherapy was used in 5/10 patients with dysgerminoma and in 17/21 patients with nondysgerminomatous tumors, with a 5-year survival of 100% for the dysgerminoma and 53% for the nondysgerminomatous group. Conclusions: Women with dysgerminoma and nondysgerminomatous tumors did not present differences regarding clinicopathologic characteristics. The prognosis for patients with dysgerminoma was better than for those with nondysgerminomatous tumors. Frozen section had a high error rate in diagnosing OGCC intraoperatively.

Original languageEnglish
Pages (from-to)450-454
Number of pages5
JournalTumori
Volume86
Issue number6
Publication statusPublished - 2000

Fingerprint

Dysgerminoma
Frozen Sections
Neoplasms
Ovarian Germ Cell Cancer
Drug Therapy
Hospital Obstetrics and Gynecology Department
Residual Neoplasm
Platinum
Gynecology
Ascites
Paraffin
Cisplatin
Brazil
Histology
Retrospective Studies
Survival

Keywords

  • Cisplatin-based chemotherapy
  • Frozen section
  • Germ cells ovarian cancer
  • Surgery

ASJC Scopus subject areas

  • Cancer Research

Cite this

Kusamura, S., Teixeira, L. C., Dos Santos, M. A., De Ângelo Andrade, L. A. L., Torres, J. C. C., Sagarra, A., ... Derchain, S. F. M. (2000). Ovarian germ cell cancer: Clinicopathologic analysis and outcome of 31 cases. Tumori, 86(6), 450-454.

Ovarian germ cell cancer : Clinicopathologic analysis and outcome of 31 cases. / Kusamura, S.; Teixeira, L. C.; Dos Santos, M. A.; De Ângelo Andrade, L. A L; Torres, J. C C; Sagarra, A.; Deraco, M.; Derchain, S. F M.

In: Tumori, Vol. 86, No. 6, 2000, p. 450-454.

Research output: Contribution to journalArticle

Kusamura, S, Teixeira, LC, Dos Santos, MA, De Ângelo Andrade, LAL, Torres, JCC, Sagarra, A, Deraco, M & Derchain, SFM 2000, 'Ovarian germ cell cancer: Clinicopathologic analysis and outcome of 31 cases', Tumori, vol. 86, no. 6, pp. 450-454.
Kusamura S, Teixeira LC, Dos Santos MA, De Ângelo Andrade LAL, Torres JCC, Sagarra A et al. Ovarian germ cell cancer: Clinicopathologic analysis and outcome of 31 cases. Tumori. 2000;86(6):450-454.
Kusamura, S. ; Teixeira, L. C. ; Dos Santos, M. A. ; De Ângelo Andrade, L. A L ; Torres, J. C C ; Sagarra, A. ; Deraco, M. ; Derchain, S. F M. / Ovarian germ cell cancer : Clinicopathologic analysis and outcome of 31 cases. In: Tumori. 2000 ; Vol. 86, No. 6. pp. 450-454.
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