Overflow microfluidic networks

Robert D. Lovchik, Fabio Bianco, Noemi Tonna, Ana Ruiz, Michela Matteoli, Emmanuel Delamarche

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Living primary cells represent the best in vitro system for studying the origin and mechanism of complex diseases. Yet these cells can be very hard to obtain, culture and study using microfluidic systems. We present here overflow microfluidic networks (oMFNs) that are particularly appropriate for studying primary cells and cellular pathways: cells are deposited on a transparent oMFN and after an appropriate culture duration in a standard cell incubator, the oMFN is sealed with a lid and excess culture medium is accommodated by capillary structures in the periphery of the chip.

Original languageEnglish
Title of host publication14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Pages989-991
Number of pages3
Volume2
Publication statusPublished - 2010
Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen, Netherlands
Duration: Oct 3 2010Oct 7 2010

Other

Other14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
CountryNetherlands
CityGroningen
Period10/3/1010/7/10

Keywords

  • Brain Disease
  • Cells
  • Microfluidics

ASJC Scopus subject areas

  • Control and Systems Engineering

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  • Cite this

    Lovchik, R. D., Bianco, F., Tonna, N., Ruiz, A., Matteoli, M., & Delamarche, E. (2010). Overflow microfluidic networks. In 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 (Vol. 2, pp. 989-991)