Overlapping representations of numerical magnitude and motion direction in the posterior parietal cortex: A TMS-adaptation study

Chiara Renzi, Tomaso Vecchi, Juha Silvanto, Zaira Cattaneo

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The human posterior parietal cortex (PPC) is involved in the encoding of both visual motion and numerical magnitude. In non human primates, neurons have been found in PPC that are selective for both motion direction and magnitude. Whether such neurons also exist in human PPC is not known. Here we investigated this hypothesis using state-dependent transcranial magnetic stimulation (TMS). Participants were adapted to a specific motion direction (either leftward or rightward), after which they performed a magnitude comparison task, with TMS applied at the onset of each trial. Our hypothesis was that neurons tuned to leftward motion may also be sensitive to small magnitudes and neurons tuned to rightward motion may also be sensitive to large magnitudes, a mapping that may have developed via spatial attentional mechanisms. Our results supported this view by showing that the effect of PPC TMS on small and large numbers depended on the motion direction being adapted, thus suggesting that there may be a functional overlap in neuronal representations of motion direction and numerical magnitude in human PPC.

Original languageEnglish
Pages (from-to)145-149
Number of pages5
JournalNeuroscience Letters
Volume490
Issue number2
DOIs
Publication statusPublished - Feb 25 2011

Fingerprint

Parietal Lobe
Transcranial Magnetic Stimulation
Neurons
Direction compound
Primates

Keywords

  • Adaptation
  • Motion processing
  • Number processing
  • Parietal cortex
  • State-dependency
  • TMS

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Overlapping representations of numerical magnitude and motion direction in the posterior parietal cortex : A TMS-adaptation study. / Renzi, Chiara; Vecchi, Tomaso; Silvanto, Juha; Cattaneo, Zaira.

In: Neuroscience Letters, Vol. 490, No. 2, 25.02.2011, p. 145-149.

Research output: Contribution to journalArticle

@article{85c36b80478840218a482bb81ddbb12a,
title = "Overlapping representations of numerical magnitude and motion direction in the posterior parietal cortex: A TMS-adaptation study",
abstract = "The human posterior parietal cortex (PPC) is involved in the encoding of both visual motion and numerical magnitude. In non human primates, neurons have been found in PPC that are selective for both motion direction and magnitude. Whether such neurons also exist in human PPC is not known. Here we investigated this hypothesis using state-dependent transcranial magnetic stimulation (TMS). Participants were adapted to a specific motion direction (either leftward or rightward), after which they performed a magnitude comparison task, with TMS applied at the onset of each trial. Our hypothesis was that neurons tuned to leftward motion may also be sensitive to small magnitudes and neurons tuned to rightward motion may also be sensitive to large magnitudes, a mapping that may have developed via spatial attentional mechanisms. Our results supported this view by showing that the effect of PPC TMS on small and large numbers depended on the motion direction being adapted, thus suggesting that there may be a functional overlap in neuronal representations of motion direction and numerical magnitude in human PPC.",
keywords = "Adaptation, Motion processing, Number processing, Parietal cortex, State-dependency, TMS",
author = "Chiara Renzi and Tomaso Vecchi and Juha Silvanto and Zaira Cattaneo",
year = "2011",
month = "2",
day = "25",
doi = "10.1016/j.neulet.2010.12.045",
language = "English",
volume = "490",
pages = "145--149",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Overlapping representations of numerical magnitude and motion direction in the posterior parietal cortex

T2 - A TMS-adaptation study

AU - Renzi, Chiara

AU - Vecchi, Tomaso

AU - Silvanto, Juha

AU - Cattaneo, Zaira

PY - 2011/2/25

Y1 - 2011/2/25

N2 - The human posterior parietal cortex (PPC) is involved in the encoding of both visual motion and numerical magnitude. In non human primates, neurons have been found in PPC that are selective for both motion direction and magnitude. Whether such neurons also exist in human PPC is not known. Here we investigated this hypothesis using state-dependent transcranial magnetic stimulation (TMS). Participants were adapted to a specific motion direction (either leftward or rightward), after which they performed a magnitude comparison task, with TMS applied at the onset of each trial. Our hypothesis was that neurons tuned to leftward motion may also be sensitive to small magnitudes and neurons tuned to rightward motion may also be sensitive to large magnitudes, a mapping that may have developed via spatial attentional mechanisms. Our results supported this view by showing that the effect of PPC TMS on small and large numbers depended on the motion direction being adapted, thus suggesting that there may be a functional overlap in neuronal representations of motion direction and numerical magnitude in human PPC.

AB - The human posterior parietal cortex (PPC) is involved in the encoding of both visual motion and numerical magnitude. In non human primates, neurons have been found in PPC that are selective for both motion direction and magnitude. Whether such neurons also exist in human PPC is not known. Here we investigated this hypothesis using state-dependent transcranial magnetic stimulation (TMS). Participants were adapted to a specific motion direction (either leftward or rightward), after which they performed a magnitude comparison task, with TMS applied at the onset of each trial. Our hypothesis was that neurons tuned to leftward motion may also be sensitive to small magnitudes and neurons tuned to rightward motion may also be sensitive to large magnitudes, a mapping that may have developed via spatial attentional mechanisms. Our results supported this view by showing that the effect of PPC TMS on small and large numbers depended on the motion direction being adapted, thus suggesting that there may be a functional overlap in neuronal representations of motion direction and numerical magnitude in human PPC.

KW - Adaptation

KW - Motion processing

KW - Number processing

KW - Parietal cortex

KW - State-dependency

KW - TMS

UR - http://www.scopus.com/inward/record.url?scp=79451475063&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79451475063&partnerID=8YFLogxK

U2 - 10.1016/j.neulet.2010.12.045

DO - 10.1016/j.neulet.2010.12.045

M3 - Article

C2 - 21193017

AN - SCOPUS:79451475063

VL - 490

SP - 145

EP - 149

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 2

ER -