TY - JOUR
T1 - Overview of potential determinants of radical prostatectomy versus radiation therapy in management of clinically localized prostate cancer: results from an Italian, prospective, observational study (the Pros-IT CNR study)
AU - group, Pros-IT CNR study
AU - Antonelli, Alessandro
AU - Palumbo, Carlotta
AU - Noale, Marianna
AU - Artibani, Walter
AU - Bassi, Pierfrancesco
AU - Bertoni, Filippo
AU - Bracarda, Sergio
AU - Bruni, Alessio
AU - Corvò, Renzo
AU - Gacci, Mauro
AU - Magrini, Stefano M.
AU - Montironi, Rodolfo
AU - Porreca, Angelo
AU - Tubaro, Andrea
AU - Zagonel, Vittorina
AU - Maggi, Stefania
N1 - Copyright: This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine
PY - 2020/10/1
Y1 - 2020/10/1
N2 - BACKGROUND: We assessed patients and tumor characteristics, as well as health-related quality of life (HRQoL) items, associated with curative intent treatment decision-making in clinically localized prostate cancer (PCa) patients. METHODS: Clinically localized PCa treated with either radical prostatectomy (RP) or radiation therapy (RT) within 12 months from diagnosis were abstracted from The PROState cancer monitoring in ITaly, from the National Research Council (Pros-IT CNR) database. Multivariable logistic regression (MLR) models predicting RT vs. RP were fitted, after adjustment for HRQoL items, patients and tumor characteristics. RESULTS: Of 1041 patients, 631 (60.2%) were treated with RP and 410 (39.8%) with RT. Relative to RT, RP patients were younger age (mean age 64.5±6.6 vs. 71.4±4.9, P
AB - BACKGROUND: We assessed patients and tumor characteristics, as well as health-related quality of life (HRQoL) items, associated with curative intent treatment decision-making in clinically localized prostate cancer (PCa) patients. METHODS: Clinically localized PCa treated with either radical prostatectomy (RP) or radiation therapy (RT) within 12 months from diagnosis were abstracted from The PROState cancer monitoring in ITaly, from the National Research Council (Pros-IT CNR) database. Multivariable logistic regression (MLR) models predicting RT vs. RP were fitted, after adjustment for HRQoL items, patients and tumor characteristics. RESULTS: Of 1041 patients, 631 (60.2%) were treated with RP and 410 (39.8%) with RT. Relative to RT, RP patients were younger age (mean age 64.5±6.6 vs. 71.4±4.9, P
U2 - 10.23736/S0393-2249.19.03637-3
DO - 10.23736/S0393-2249.19.03637-3
M3 - Article
VL - 72
SP - 595
EP - 604
JO - Minerva Urologica e Nefrologica
JF - Minerva Urologica e Nefrologica
SN - 0393-2249
IS - 5
ER -