Ozone air pollution and daily mortality in Genoa, Italy between 1993 and 1996

Stefano Parodi, M. Vercelli, E. Garrone, V. Fontana, A. Izzotti

Research output: Contribution to journalArticlepeer-review


The association between ozone (O3) and daily mortality was investigated in Genoa, an Italian city characterized by a Mediterranean climate and a high prevalence of elderly inhabitants. The O3 effect, adjusted for long time trend, seasonality and weather, was assessed using Poisson regression modelling, allowing for overdispersion and autocorrelation, and expressed as mean variation percent of daily mortality per 50 μg/m3 increase (MV). Significant MVs for overall (+4.0%) and cardiovascular (+7.2%) mortality were detected at 1-day lag. The effects were stronger in the warmer season (May-October). Similar estimates were found after restricting the analyses to the elderly (≥75 years). Furthermore, in this group, higher MVs were observed for total mortality at 2-day lag. A statistically significant synergistic effect between O3 and temperature was observed for cardiovascular mortality, particularly in elderly people, with an evident increase in mortality risk above 26 °C (MV +30.0% for the whole population and +40.0% for the elderly, respectively). This investigation highlights the importance of taking local climatic and demographic features into account when comparing different time-series studies, and substantiates the influence of photochemical pollution on mortality trends in small urban areas.

Original languageEnglish
Pages (from-to)844-850
Number of pages7
JournalPublic Health
Issue number9
Publication statusPublished - Sep 2005


  • Air pollution
  • Elderly
  • Mortality
  • Ozone
  • Time-series analysis

ASJC Scopus subject areas

  • Health(social science)


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