TY - JOUR
T1 - Ozone chemonucleolysis in non-contained lumbar disc herniations
T2 - a pilot study with 12 months follow-up.
AU - Buric, J.
AU - Molino Lova, R.
PY - 2005
Y1 - 2005
N2 - STUDY DESIGN: Prospective case series with six and twelve months follow up. OBJECTIVE: To observe clinical and morphological results of the intradiscal ozone chemionucleolysis in patients affected by non-contained lumbar disc herniations. METHODS: 30 patients were included in the study on the base of precise inclusion and exclusion criteria. The patients were followed on 6 and 12 months period by Visual Analogic Scale (VAS), Roland Morris Disability Questionnaire (RMDQ) and Overall Patient Rating Scale (OPRS). Disc herniation volume morphology was evaluated at 5 months by control MRI scanning. RESULTS: Twenty-seven patients (90%) showed a statistically significant improvement in pain (P <0.001, Wilcoxon test) and function (P <0.001, Wilcoxon test), on VAS and RMDQ evaluation, respectively. The mean satisfaction with the treatment on OPSR was 79.3%, with 24 patients referring satisfaction equal or greater than 80%. There were no major complications related to the procedure. CONCLUSIONS: The results of this study indicate the ozone chemonucleolysis as a possibly effective modality of treatment in patients affected by signs and symptoms of non-contained lumbar disc herniations that have overpassed conservative measures and have not yet fulfilled the indications for open surgical treatment.
AB - STUDY DESIGN: Prospective case series with six and twelve months follow up. OBJECTIVE: To observe clinical and morphological results of the intradiscal ozone chemionucleolysis in patients affected by non-contained lumbar disc herniations. METHODS: 30 patients were included in the study on the base of precise inclusion and exclusion criteria. The patients were followed on 6 and 12 months period by Visual Analogic Scale (VAS), Roland Morris Disability Questionnaire (RMDQ) and Overall Patient Rating Scale (OPRS). Disc herniation volume morphology was evaluated at 5 months by control MRI scanning. RESULTS: Twenty-seven patients (90%) showed a statistically significant improvement in pain (P <0.001, Wilcoxon test) and function (P <0.001, Wilcoxon test), on VAS and RMDQ evaluation, respectively. The mean satisfaction with the treatment on OPSR was 79.3%, with 24 patients referring satisfaction equal or greater than 80%. There were no major complications related to the procedure. CONCLUSIONS: The results of this study indicate the ozone chemonucleolysis as a possibly effective modality of treatment in patients affected by signs and symptoms of non-contained lumbar disc herniations that have overpassed conservative measures and have not yet fulfilled the indications for open surgical treatment.
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M3 - Article
C2 - 15830976
AN - SCOPUS:18044383723
VL - 92
SP - 93
EP - 97
JO - Acta Neurochirurgica, Supplement
JF - Acta Neurochirurgica, Supplement
SN - 0065-1419
ER -