Gli anticorpi p-ANCA ed ASCA nella diagnosi differenziale fra rettocolite ulcerosa e malattia di Crohn

Translated title of the contribution: p-ANCA and ASCA antibodies and the differential diagnosis between ulcerative colitis and Crohn's disease

Pierenrico Lecis, Bastianello Germanà, Nunziato Papa, Gianni Bertiato, Claudio Doglioni, Ermenegildo Galliani, Franco Costan Biedo

Research output: Contribution to journalArticle

Abstract

Anti-Saccaromyces cerevisiae antibodies (ASCA) seem to be associated with Crohn's disease (CD), while anti-neutrophil cytoplasm antibodies (p-ANCA) seem to be a recognised marker for ulcerative colitis (UC). Aim of our study was to determine whether the presence of ASCA and p-ANCA antibodies could differentiate CD from UC and IBD from aspecific chronic colitis (ACC). Methods: serum samples were obtained from 23 patients with CD and 32 with UC, and from 13 patients with aspecific chronic colitis. Diagnosis was established on clinical findings, endoscopy and histology. Determination of ASCA and p-ANCA antibodies was performed using indirect immunofluorescence technique and ELISA, respectively. Results: 20% CD patients against 50% UC patients expressed p-ANCA (p

Original languageItalian
Pages (from-to)308-313
Number of pages6
JournalRecenti Progressi in Medicina
Volume93
Issue number5
Publication statusPublished - May 2002

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Antineutrophil Cytoplasmic Antibodies
Ulcerative Colitis
Crohn Disease
Differential Diagnosis
Antibodies
Colitis
Indirect Fluorescent Antibody Technique
Endoscopy
Histology
Cytoplasm
Neutrophils
Enzyme-Linked Immunosorbent Assay
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lecis, P., Germanà, B., Papa, N., Bertiato, G., Doglioni, C., Galliani, E., & Biedo, F. C. (2002). Gli anticorpi p-ANCA ed ASCA nella diagnosi differenziale fra rettocolite ulcerosa e malattia di Crohn. Recenti Progressi in Medicina, 93(5), 308-313.

Gli anticorpi p-ANCA ed ASCA nella diagnosi differenziale fra rettocolite ulcerosa e malattia di Crohn. / Lecis, Pierenrico; Germanà, Bastianello; Papa, Nunziato; Bertiato, Gianni; Doglioni, Claudio; Galliani, Ermenegildo; Biedo, Franco Costan.

In: Recenti Progressi in Medicina, Vol. 93, No. 5, 05.2002, p. 308-313.

Research output: Contribution to journalArticle

Lecis, P, Germanà, B, Papa, N, Bertiato, G, Doglioni, C, Galliani, E & Biedo, FC 2002, 'Gli anticorpi p-ANCA ed ASCA nella diagnosi differenziale fra rettocolite ulcerosa e malattia di Crohn', Recenti Progressi in Medicina, vol. 93, no. 5, pp. 308-313.
Lecis, Pierenrico ; Germanà, Bastianello ; Papa, Nunziato ; Bertiato, Gianni ; Doglioni, Claudio ; Galliani, Ermenegildo ; Biedo, Franco Costan. / Gli anticorpi p-ANCA ed ASCA nella diagnosi differenziale fra rettocolite ulcerosa e malattia di Crohn. In: Recenti Progressi in Medicina. 2002 ; Vol. 93, No. 5. pp. 308-313.
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