Abstract
Anti-Saccaromyces cerevisiae antibodies (ASCA) seem to be associated with Crohn's disease (CD), while anti-neutrophil cytoplasm antibodies (p-ANCA) seem to be a recognised marker for ulcerative colitis (UC). Aim of our study was to determine whether the presence of ASCA and p-ANCA antibodies could differentiate CD from UC and IBD from aspecific chronic colitis (ACC). Methods: serum samples were obtained from 23 patients with CD and 32 with UC, and from 13 patients with aspecific chronic colitis. Diagnosis was established on clinical findings, endoscopy and histology. Determination of ASCA and p-ANCA antibodies was performed using indirect immunofluorescence technique and ELISA, respectively. Results: 20% CD patients against 50% UC patients expressed p-ANCA (p
| Original language | Italian |
|---|---|
| Pages (from-to) | 308-313 |
| Number of pages | 6 |
| Journal | Recenti Progressi in Medicina |
| Volume | 93 |
| Issue number | 5 |
| Publication status | Published - May 2002 |
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Gli anticorpi p-ANCA ed ASCA nella diagnosi differenziale fra rettocolite ulcerosa e malattia di Crohn. / Lecis, Pierenrico; Germanà, Bastianello; Papa, Nunziato; Bertiato, Gianni; Doglioni, Claudio; Galliani, Ermenegildo; Biedo, Franco Costan.
In: Recenti Progressi in Medicina, Vol. 93, No. 5, 05.2002, p. 308-313.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Gli anticorpi p-ANCA ed ASCA nella diagnosi differenziale fra rettocolite ulcerosa e malattia di Crohn
AU - Lecis, Pierenrico
AU - Germanà, Bastianello
AU - Papa, Nunziato
AU - Bertiato, Gianni
AU - Doglioni, Claudio
AU - Galliani, Ermenegildo
AU - Biedo, Franco Costan
PY - 2002/5
Y1 - 2002/5
N2 - Anti-Saccaromyces cerevisiae antibodies (ASCA) seem to be associated with Crohn's disease (CD), while anti-neutrophil cytoplasm antibodies (p-ANCA) seem to be a recognised marker for ulcerative colitis (UC). Aim of our study was to determine whether the presence of ASCA and p-ANCA antibodies could differentiate CD from UC and IBD from aspecific chronic colitis (ACC). Methods: serum samples were obtained from 23 patients with CD and 32 with UC, and from 13 patients with aspecific chronic colitis. Diagnosis was established on clinical findings, endoscopy and histology. Determination of ASCA and p-ANCA antibodies was performed using indirect immunofluorescence technique and ELISA, respectively. Results: 20% CD patients against 50% UC patients expressed p-ANCA (p
AB - Anti-Saccaromyces cerevisiae antibodies (ASCA) seem to be associated with Crohn's disease (CD), while anti-neutrophil cytoplasm antibodies (p-ANCA) seem to be a recognised marker for ulcerative colitis (UC). Aim of our study was to determine whether the presence of ASCA and p-ANCA antibodies could differentiate CD from UC and IBD from aspecific chronic colitis (ACC). Methods: serum samples were obtained from 23 patients with CD and 32 with UC, and from 13 patients with aspecific chronic colitis. Diagnosis was established on clinical findings, endoscopy and histology. Determination of ASCA and p-ANCA antibodies was performed using indirect immunofluorescence technique and ELISA, respectively. Results: 20% CD patients against 50% UC patients expressed p-ANCA (p
KW - ASCA
KW - Crohn's disease
KW - p-ANCA
KW - Serological markers
KW - Ulcerative colitis
UR - http://www.scopus.com/inward/record.url?scp=0036582020&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036582020&partnerID=8YFLogxK
M3 - Articolo
C2 - 12050913
AN - SCOPUS:0036582020
VL - 93
SP - 308
EP - 313
JO - Recenti Progressi in Medicina
JF - Recenti Progressi in Medicina
SN - 0034-1193
IS - 5
ER -