Abstract
Anti-Saccaromyces cerevisiae antibodies (ASCA) seem to be associated with Crohn's disease (CD), while anti-neutrophil cytoplasm antibodies (p-ANCA) seem to be a recognised marker for ulcerative colitis (UC). Aim of our study was to determine whether the presence of ASCA and p-ANCA antibodies could differentiate CD from UC and IBD from aspecific chronic colitis (ACC). Methods: serum samples were obtained from 23 patients with CD and 32 with UC, and from 13 patients with aspecific chronic colitis. Diagnosis was established on clinical findings, endoscopy and histology. Determination of ASCA and p-ANCA antibodies was performed using indirect immunofluorescence technique and ELISA, respectively. Results: 20% CD patients against 50% UC patients expressed p-ANCA (p
Translated title of the contribution | p-ANCA and ASCA antibodies and the differential diagnosis between ulcerative colitis and Crohn's disease |
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Original language | Italian |
Pages (from-to) | 308-313 |
Number of pages | 6 |
Journal | Recenti Progressi in Medicina |
Volume | 93 |
Issue number | 5 |
Publication status | Published - May 2002 |
ASJC Scopus subject areas
- Medicine(all)