Abstract
The p53 oncosuppressor is the gene which has been found to be most frequently altered in human cancers. How the p53 gene contributes to tumor induction and progression is presently being investigated by numerous researchers whose specialties range from basic science to clinics. This is a brief overview of the hypotheses on p53 role in tumorigenesis and the possible use of p53 analyses in tumor prognosis and therapy.
| Original language | English |
|---|---|
| Pages (from-to) | 237-242 |
| Number of pages | 6 |
| Journal | Journal of Experimental and Clinical Cancer Research |
| Volume | 16 |
| Issue number | 3 |
| Publication status | Published - Sep 1997 |
Keywords
- Apoptosis
- Genome stability
- Oncosuppressor
- P53
- Tumor progression
ASJC Scopus subject areas
- Cancer Research
- Oncology