TY - JOUR
T1 - p63 in Squamous Cell Carcinoma of the Skin
T2 - More Than a Stem Cell/Progenitor Marker
AU - Missero, Caterina
AU - Antonini, Dario
PY - 2017/2/1
Y1 - 2017/2/1
N2 - The p63 gene is often overexpressed in squamous cell carcinomas; however, how its overexpression contributes to tumor formation and expansion is still incompletely understood. Devos et al. report the development of a versatile mouse model demonstrating that p63 facilitates squamous cell carcinoma formation in skin and providing an excellent tool to dissect the relevance of its downstream signaling pathways in tumorigenesis.
AB - The p63 gene is often overexpressed in squamous cell carcinomas; however, how its overexpression contributes to tumor formation and expansion is still incompletely understood. Devos et al. report the development of a versatile mouse model demonstrating that p63 facilitates squamous cell carcinoma formation in skin and providing an excellent tool to dissect the relevance of its downstream signaling pathways in tumorigenesis.
UR - http://www.scopus.com/inward/record.url?scp=85010404044&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85010404044&partnerID=8YFLogxK
U2 - 10.1016/j.jid.2016.10.032
DO - 10.1016/j.jid.2016.10.032
M3 - Comment/debate
C2 - 28110711
AN - SCOPUS:85010404044
VL - 137
SP - 280
EP - 281
JO - Journal of Investigative Dermatology
JF - Journal of Investigative Dermatology
SN - 0022-202X
IS - 2
ER -