p63 in Squamous Cell Carcinoma of the Skin: More Than a Stem Cell/Progenitor Marker

Caterina Missero, Dario Antonini

Research output: Contribution to journalComment/debatepeer-review

Abstract

The p63 gene is often overexpressed in squamous cell carcinomas; however, how its overexpression contributes to tumor formation and expansion is still incompletely understood. Devos et al. report the development of a versatile mouse model demonstrating that p63 facilitates squamous cell carcinoma formation in skin and providing an excellent tool to dissect the relevance of its downstream signaling pathways in tumorigenesis.

Original languageEnglish
Pages (from-to)280-281
Number of pages2
JournalJournal of Investigative Dermatology
Volume137
Issue number2
DOIs
Publication statusPublished - Feb 1 2017

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

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