Abstract
Oxygen metabolism is thought to impact on aging through the formation of reactive oxygen species (ROS) that are supposed to damage biological molecules. The study of p66(Shc), a crucial regulator of ROS level involved in aging dysfunction, suggests that the incidence of degenerative disease and longevity are determined by a specific signaling function of ROS other than their unspecific damaging property.
Original language | English |
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Pages (from-to) | 503-510 |
Number of pages | 8 |
Journal | Aging |
Volume | 1 |
Issue number | 6 |
Publication status | Published - Jun 2009 |
ASJC Scopus subject areas
- Geriatrics and Gerontology