PACE continuous innovation indicators-A novel tool to measure progress in cancer treatments

Silvia Paddock, Lauren Brum, Kathleen Sorrow, Samuel Thomas, Susan Spence, Catharina Maulbecker-Armstrong, Clifford Goodman, Michael Peake, Gordon McVie, Gary Geipel, Rose Li

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Concerns about rising health care costs and the often incremental nature of improvements in health outcomes continue to fuel intense debates about 'progress' and 'value' in cancer research. In times of tightening fiscal constraints, it is increasingly important for patients and their representatives to define what constitutes 'value' to them. It is clear that diverse stakeholders have different priorities. Harmonisation of values may be neither possible nor desirable. Stakeholders lack tools to visualise or otherwise express these differences and to track progress in cancer treatments based on variable sets of values. The Patient Access to Cancer care Excellence (PACE) Continuous Innovation Indicators are novel, scientifically rigorous progress trackers that employ a three-step process to quantify progress in cancer treatments: 1) mine the literature to determine the strength of the evidence supporting each treatment; 2) allow users to weight the analysis according to their priorities and values; and 3) calculate Evidence Scores (E-Scores), a novel measure to track progress, based on the strength of the evidence weighted by the assigned value. We herein introduce a novel, flexible value model, show how the values from the model can be used to weight the evidence from the scientific literature to obtain E-Scores, and illustrate how assigning different values to new treatments influences the E-Scores.

Original languageEnglish
Pages (from-to)1-30
Number of pages30
Journalecancermedicalscience
Volume9
DOIs
Publication statusPublished - Jan 7 2015

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Neoplasms
Literature
Patient Advocacy
Weights and Measures
Therapeutics
Health Care Costs
Health
Research

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Paddock, S., Brum, L., Sorrow, K., Thomas, S., Spence, S., Maulbecker-Armstrong, C., ... Li, R. (2015). PACE continuous innovation indicators-A novel tool to measure progress in cancer treatments. ecancermedicalscience, 9, 1-30. https://doi.org/10.3332/ecancer.2015.498

PACE continuous innovation indicators-A novel tool to measure progress in cancer treatments. / Paddock, Silvia; Brum, Lauren; Sorrow, Kathleen; Thomas, Samuel; Spence, Susan; Maulbecker-Armstrong, Catharina; Goodman, Clifford; Peake, Michael; McVie, Gordon; Geipel, Gary; Li, Rose.

In: ecancermedicalscience, Vol. 9, 07.01.2015, p. 1-30.

Research output: Contribution to journalArticle

Paddock, S, Brum, L, Sorrow, K, Thomas, S, Spence, S, Maulbecker-Armstrong, C, Goodman, C, Peake, M, McVie, G, Geipel, G & Li, R 2015, 'PACE continuous innovation indicators-A novel tool to measure progress in cancer treatments', ecancermedicalscience, vol. 9, pp. 1-30. https://doi.org/10.3332/ecancer.2015.498
Paddock S, Brum L, Sorrow K, Thomas S, Spence S, Maulbecker-Armstrong C et al. PACE continuous innovation indicators-A novel tool to measure progress in cancer treatments. ecancermedicalscience. 2015 Jan 7;9:1-30. https://doi.org/10.3332/ecancer.2015.498
Paddock, Silvia ; Brum, Lauren ; Sorrow, Kathleen ; Thomas, Samuel ; Spence, Susan ; Maulbecker-Armstrong, Catharina ; Goodman, Clifford ; Peake, Michael ; McVie, Gordon ; Geipel, Gary ; Li, Rose. / PACE continuous innovation indicators-A novel tool to measure progress in cancer treatments. In: ecancermedicalscience. 2015 ; Vol. 9. pp. 1-30.
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