Paclitaxel-eluting stents

John Cosgrave; Corbett Simon; Rade Babic; Antonio Colombo

doi:10.2217/14796678.2.2.229

Paclitaxel-eluting stents

John Cosgrave, Corbett Simon, Rade Babic, Antonio Colombo

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Percutaneous coronary intervention and stent implantation is rapidly becoming the most commonly used form of revascularization. The long term results of this procedure are limited by restenosis which is a phenomenon predominantly caused by proliferation of smooth muscle cells. Many devices and pharmaceutical agents have been unsuccessful in preventing this problem. Paclitaxel is an antiproliferative drug that has been extensively studied for the prevention of restenosis. This article will review the trial results of the currently available stent platforms and discuss some of the ongoing studies and future directions for the development of new paclitaxel-eluting stents.

Original language	English
Pages (from-to)	229-239
Number of pages	11
Journal	Future Cardiology
Volume	2
Issue number	2
DOIs	https://doi.org/10.2217/14796678.2.2.229
Publication status	Published - Feb 2006

Keywords

Major adverse cardiac events
Paclitaxel-eluting stent
Restenosis
Revascularization

ASJC Scopus subject areas

Molecular Medicine
Cardiology and Cardiovascular Medicine

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10.2217/14796678.2.2.229

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Paclitaxel-eluting stents

Abstract

Keywords

ASJC Scopus subject areas

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