Paget's disease of the vulva is a rare, chronically recurrent neoplastic disease of the skin and cutaneous adnexa, affecting postmenopausal women and characterized by long lasting local discomfort. It is rarely a secondary manifestation of an adenocarcinoma arising from other adjacent sites. Histological examination of multiples specimens is necessary to exclude invasion to deeper layers and the malignant pattern. Wide surgical excision is the treatment of choice, even if an high rate of recurrences must be expected. In recurrent cases, topical imiquimod applications represent a valid option with satisfactory cure rates.
|Translated title of the contribution||Paget's disease of the vulva. Case report|
|Number of pages||3|
|Journal||Italian Journal of Gynaecology and Obstetrics|
|Publication status||Published - 2012|
ASJC Scopus subject areas
- Obstetrics and Gynaecology