Pain in Amyotrophic Lateral Sclerosis: A psychological perspective

Francesco Pagnini, Christian Lunetta, Paolo Banfi, Gabriella Rossi, Federica Fossati, Anna Marconi, Gianluca Castelnuovo, Massimo Corbo, Enrico Molinari

Research output: Contribution to journalArticlepeer-review


Pain in Amyotrophic Lateral Sclerosis is often underestimated and untreated by clinicians and few studies have investigated its specific features and impact. Pain experience was investigated with the Italian Questionnaire of Pain, together with the McGill Quality of Life Questionnaire for quality of life (QoL), at a baseline and at a 4-month follow-up. About half of ALS patients reported pain, described as nagging, sore, annoying, boring and exhausting, with periodic but enduring episodes. Pain was related with QoL and its intensity was able to predict QoL worsening. Obtained results indicate the importance of clinical investigation of pain in ALS patients and of the intervention with anti-pain treatment whenever necessary.

Original languageEnglish
Pages (from-to)1193-1196
Number of pages4
JournalNeurological Sciences
Issue number5
Publication statusPublished - Oct 2012


  • Amyotrophic Lateral Sclerosis
  • Pain
  • Quality of Life

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology


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