Palatability of angiotensin II antagonists among nephropathic children

Chiara M. Meier, Giacomo D. Simonetti, Silvia Ghiglia, Emilio Fossali, Patrizia Salice, Costanzo Limoni, Mario G. Bianchetti

Research output: Contribution to journalArticle

Abstract

Aim: Angiotensin II receptor blockers are widely prescribed in kidney disease. Among children, medication palatability is crucial for adherence. Methods: Taste and smell acceptability of five angiotensin II receptor blockers were compared among 21 nephropathic children using a visual analogue scale palatability score. Results: The score assigned to pulverized tablets of candesartan cilexetil was significantly higher than that assigned to pulverized tablets of irbesartan, losartan, telmisartan and valsartan. Conclusions: From the perspective of the nephropathic child, the taste of pulverized candesartan cilexetil is superior to that of irbesartan, losartan, telmisartan or valsartan.

Original languageEnglish
Pages (from-to)628-631
Number of pages4
JournalBritish Journal of Clinical Pharmacology
Volume63
Issue number5
DOIs
Publication statusPublished - May 2007

Keywords

  • Candesartan cilexetil
  • Hypertension
  • Irbesartan
  • Losartan
  • Palatability
  • Telmisartan
  • Valsartan

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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