Pancreas disease and diabetes mellitus

The main disease concerning the endocrine function of the pancreas is diabetes mellitus. Cutaneous manifestations are common in diabetes mellitus, with approximately 30% of patients experiencing some cutaneous involvement during the course of their illness. They can be classified as (1) non-infectious, including diseases with strong and weak associations with diabetes; (2) infectious; (3) related to complications because of vasculopathy and neuropathy; (4) related to complications of diabetes treatment. Skin manifestations generally appear during the course of diabetes but they may be first presenting sign or even precede the diagnosis of diabetes by many years. Patients with type 2 diabetes are more prone to develop skin infections, whereas those with type 1 more often have autoimmune-related diseases.