TY - JOUR
T1 - Pancreas preservation with university of wisconsin and celsior solutions
AU - Boggi, U.
AU - Coletti, L.
AU - Vistoli, F.
AU - Del Chiaro, M.
AU - Signori, S.
AU - Croce, C.
AU - Bartolo, T. Vanadia
AU - Pietrabissa, A.
AU - Marchetti, P.
AU - Capocasale, E.
AU - Dalla Valle, R.
AU - Mazzoni, M. P.
AU - Mosca, F.
PY - 2004/4
Y1 - 2004/4
N2 - Background Although the use of Celsior has been recently described for heart, lung, liver, and kidney transplantation, no data are available on its use for clinical pancreas preservation. Methods We herein describe the results of 112 pancreas transplants preserved with either University of Wisconsin (UW; (n = 56) or Celsior (n = 56) solution at two Italian transplant centers. The groups were comparable with regard to all donor and recipient characteristics. Results Mean cold and warm ischemia times were 10.1 ± 2.2 hours and 37.2 ± 8.2 minutes for UW compared to 10.8 ± 2.4 hours and 38.3 ± 6.7 minutes for Celsior (P = NS). Delayed endocrine pancreas function was recorded in two UW-preserved grafts (3.6%). Actuarial 1-year patient survival was 94.6% for UW as compared with 100% for Celsior (P = NS). Equivalent graft survival figures were 91.0% for UW as compared with 96.4% for Celsior (P = NS). Conclusions Within the range of cold ischemia times reported in this study, UW and Celsior solutions have similar safety profiles for pancreas transplantation.
AB - Background Although the use of Celsior has been recently described for heart, lung, liver, and kidney transplantation, no data are available on its use for clinical pancreas preservation. Methods We herein describe the results of 112 pancreas transplants preserved with either University of Wisconsin (UW; (n = 56) or Celsior (n = 56) solution at two Italian transplant centers. The groups were comparable with regard to all donor and recipient characteristics. Results Mean cold and warm ischemia times were 10.1 ± 2.2 hours and 37.2 ± 8.2 minutes for UW compared to 10.8 ± 2.4 hours and 38.3 ± 6.7 minutes for Celsior (P = NS). Delayed endocrine pancreas function was recorded in two UW-preserved grafts (3.6%). Actuarial 1-year patient survival was 94.6% for UW as compared with 100% for Celsior (P = NS). Equivalent graft survival figures were 91.0% for UW as compared with 96.4% for Celsior (P = NS). Conclusions Within the range of cold ischemia times reported in this study, UW and Celsior solutions have similar safety profiles for pancreas transplantation.
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U2 - 10.1016/j.transproceed.2004.03.078
DO - 10.1016/j.transproceed.2004.03.078
M3 - Article
C2 - 15110594
AN - SCOPUS:11144355047
VL - 36
SP - 563
EP - 565
JO - Transplantation Proceedings
JF - Transplantation Proceedings
SN - 0041-1345
IS - 3
ER -