Pancreatic pseudocysts: Prognostic factors for their development and their spontaneous resolution in the setting of acute pancreatitis

Paul Georg Lankisch, Bettina Weber-Dany, Patrick Maisonneuve, Albert B. Lowenfels

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26 Citations (Scopus)

Abstract

Background and aim: Previous studies on the development of pancreatic pseudocysts following acute pancreatitis were monocentric, mostly retrospective, did not fulfil the Atlanta criteria, and featured a mixture of patients with post-acute and chronic pancreatitis. Therefore, the natural course of pancreatic pseudocysts after acute pancreatitis and the reasons for their spontaneous resolution remain unknown. Methods: This prospective study of 369 patients investigated the prognostic factors for development of pancreatic pseudocysts and for their spontaneous resolution after a first episode of acute pancreatitis. Results: On discharge, 124 (34%) patients still had pancreatic fluid collections. The prognostic factor for these fluid collections was severe acute pancreatitis. Follow-up examination 3 and 6 months later showed pancreatic pseudocysts in 36 (10%) patients (30 with and 6 without prior fluid collection), and in 27 (7%) patients (25 with and 2 without pancreatic pseudocyst after 3 months), respectively. The prognostic factors for their development were alcohol abuse and an initial severe course of the disease. Spontaneous complete resolution of the pancreatic pseudocysts occurred in 11 (31%) of the 36 patients. Prognostic factors for the spontaneous resolution were no or mild symptoms (nausea, vomiting, abdominal pain) and a maximal cyst diameter of

Original languageEnglish
Pages (from-to)85-90
Number of pages6
JournalPancreatology
Volume12
Issue number2
DOIs
Publication statusPublished - Mar 2012

Fingerprint

Pancreatic Pseudocyst
Pancreatitis
Chronic Pancreatitis
Nausea
Abdominal Pain
Alcoholism
Vomiting
Cysts
Prospective Studies

Keywords

  • Acute pancreatitis - clinical aspects
  • Acute pancreatitis - management
  • Acute pancreatitis - prognostic factors
  • Clinical studies
  • Pancreatic disease- clinical

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Hepatology

Cite this

Pancreatic pseudocysts : Prognostic factors for their development and their spontaneous resolution in the setting of acute pancreatitis. / Lankisch, Paul Georg; Weber-Dany, Bettina; Maisonneuve, Patrick; Lowenfels, Albert B.

In: Pancreatology, Vol. 12, No. 2, 03.2012, p. 85-90.

Research output: Contribution to journalArticle

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