Pancreaticoduodenectomy for pancreatic metastases from breast carcinoma

Stefano Crippa, Claudia Bonardi, Giorgio Bovo, Chiara Mussi, Carlo Angelini, Franco Uggeri

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Context: Unlike primary pancreatic carcinoma, metastases to the pancreas are rare events and their resection may be performed as a palliative treatment. The aim of this study was to review our experience with the operative management of pancreatic metastase from breast carcinoma. Case report: Three patients underwent pancreaticoduodenectomy for pancreatic metastases from breast carcinoma between 1990 and 2002. The Clinical features of and the results after resection were examined. The presenting clinical symptoms were jaundice, pain and weight loss. In all cases, the pancreatic metastases were solitary lesions located in the head of the pancreas and the intervals between the primary breast carcinoma and the pancreatic metastases were 3, 5 and 7 years. The primary tumor was lobular carcinoma. Metastases were initially misdiagnosed as primary cancers. All patients underwent pancreaticoduodenectomy. One patient died from disseminated metastatic disease 26 months after surgery. The other two patients are alive 37 and 21 months after pancreaticoduodenectomy; the second one has had recurrence of the disease. Conclusion: In rare cases, the pancreas may be the presenting site for breast metastases, typically years after treating the primary tumor. Pancreaticoduodenectomy can be performed in the absence of extreme metastatic disease; it can provide worthwhile palliation and improve survival.

Original languageEnglish
Pages (from-to)377-383
Number of pages7
JournalJournal of the Pancreas
Volume5
Issue number5
Publication statusPublished - Sep 2004

Fingerprint

Pancreaticoduodenectomy
Breast Neoplasms
Neoplasm Metastasis
Pancreas
Lobular Carcinoma
Neoplasms
Jaundice
Diagnostic Errors
Palliative Care
Weight Loss
Breast
Recurrence
Pain
Survival

Keywords

  • Breast neoplasms
  • Neoplasm metastasis
  • Pancreatic neoplasms

ASJC Scopus subject areas

  • Endocrinology
  • Gastroenterology

Cite this

Crippa, S., Bonardi, C., Bovo, G., Mussi, C., Angelini, C., & Uggeri, F. (2004). Pancreaticoduodenectomy for pancreatic metastases from breast carcinoma. Journal of the Pancreas, 5(5), 377-383.

Pancreaticoduodenectomy for pancreatic metastases from breast carcinoma. / Crippa, Stefano; Bonardi, Claudia; Bovo, Giorgio; Mussi, Chiara; Angelini, Carlo; Uggeri, Franco.

In: Journal of the Pancreas, Vol. 5, No. 5, 09.2004, p. 377-383.

Research output: Contribution to journalArticle

Crippa, S, Bonardi, C, Bovo, G, Mussi, C, Angelini, C & Uggeri, F 2004, 'Pancreaticoduodenectomy for pancreatic metastases from breast carcinoma', Journal of the Pancreas, vol. 5, no. 5, pp. 377-383.
Crippa S, Bonardi C, Bovo G, Mussi C, Angelini C, Uggeri F. Pancreaticoduodenectomy for pancreatic metastases from breast carcinoma. Journal of the Pancreas. 2004 Sep;5(5):377-383.
Crippa, Stefano ; Bonardi, Claudia ; Bovo, Giorgio ; Mussi, Chiara ; Angelini, Carlo ; Uggeri, Franco. / Pancreaticoduodenectomy for pancreatic metastases from breast carcinoma. In: Journal of the Pancreas. 2004 ; Vol. 5, No. 5. pp. 377-383.
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