Pancreatitis and portal vein thrombosis in children: The chicken or the egg causality dilemma

Fabrizio Di Francesco, Laura Del Prete, Chiara Grimaldi, Lidia Monti, Jean De Ville De Goyet

Research output: Contribution to journalArticlepeer-review


Background The association of pancreatitis and portal vein thrombosis (PVT) is extremely rare in children. We report on 3 cases which suggest that there may be a causal relation between the two. Methods Clinical characteristics and evolution of 3 children with this particular condition were analyzed retrospectively. In this group of patients, the strategy consisted in opting for early surgical decompression of the portal hypertension, which was followed by a favorable outcome, not only in terms of complications related to the portal hypertension but also of a contemporaneous spontaneous regression of the concurrent pancreatic disease, in absence of any other specific management of the latter problem. Results and conclusions Combined PVT and pancreatitis is exceptional in children. Although this series is small, it provides insight and some evidence that the pancreatic disease might be secondary to the cavernomatous transformation of the regional venous system. More interestingly, it suggests that the appropriate management strategy should be to rapidly relieve portal hypertension after resolution of the acute phase of pancreatitis.

Original languageEnglish
Pages (from-to)565-569
Number of pages5
JournalJournal of Pediatric Surgery
Issue number4
Publication statusPublished - Apr 1 2015


  • Children
  • Meso-Rex bypass
  • Pancreatitis
  • Portal hypertension
  • Surgical strategy

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health
  • Medicine(all)


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