Panel Reactive Antibody Monitoring in Pediatric Patients Undergoing Ventricle Assist Device as a Bridge to Heart Transplantation

Research output: Contribution to journalArticle

Abstract

We describe the incidence and patterns of anti-human leukocyte antigens antibody production in a pediatric population undergoing ventricular assist device (VAD) implantation. Serial panel reactive antibody was obtained prior to VAD implant, during VAD support, and after orthotopic heart transplantation (OHT). Seven children (median age 15 months) underwent VAD support as bridge to OHT. Posttransplant sensitization occurred in 42% of VAD patients and in 14% during VAD support.

Original languageEnglish
Pages (from-to)435-438
Number of pages4
JournalArtificial Organs
Volume37
Issue number5
DOIs
Publication statusPublished - May 2013

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Keywords

  • Panel reactive antibody
  • Pediatric heart transplantation
  • Sensitization
  • Ventricle assist device

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Bioengineering
  • Medicine (miscellaneous)

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