Papillary carcinoma in struma ovarii: A case report

Nataniele Piol, Bruno Spina, Massimo Giusti, Simone Ferrero, Carlo Toncini, Valerio Gaetano Vellone

Research output: Contribution to journalArticlepeer-review


BACKGROUND: Thyroid-type carcinoma in struma ovarii (SO) is a very rare neoplasia which can sometimes be difficult to diagnose and treat because of the relatively poor knowledge of the disease. CASE: A 52-year-old woman with a right ovarian neoformation presented with abdominopelvic pain. A bilateral salpingo-oophorectomy was performed, and histopathological examination revealed a right ovarian teratoma in which thyroid tissue harbored a nonencapsulated follicular variant of papillary carcinoma. Total thyroidectomy ruled out metastasis from a primary thyroid tumor, and histopathological examination revealed no evidence of thyroid malignancy. Radioactive iodine therapy was performed 4 months after thyroidectomy, and the patient showed no evidence of recurrent or persistent disease after 14 months of follow-up. CONCLUSION: Papillary thyroid-type carcinoma is reported as the most common thyroid-type carcinoma in SO and yet is a very rare disease, with only 18 cases reported in the English literature in the last 9 years. No consensus has been reached among pathologists in diagnostic criteria nor among clinicians in treatment strategy. CONCLUSION: As thyroid-type carcinoma in SO is a rare disease, much effort is needed in developing adequate diagnostic criteria and treatment modalities.

Original languageEnglish
Pages (from-to)100-105
Number of pages6
JournalAnalytical and Quantitative Cytopathology and Histopathology
Issue number2
Publication statusPublished - Apr 1 2018


  • Carcinoma
  • Ovarian cancer
  • Ovarian diseases
  • Ovarian teratoma
  • Ovary
  • Papillary
  • Rare diseases
  • Struma ovarii
  • Thyroid cancer
  • Thyroid neoplasms

ASJC Scopus subject areas

  • Histology
  • Pathology and Forensic Medicine
  • Cell Biology


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