TY - JOUR
T1 - Papillary thyroid carcinoma in pediatric age
T2 - An example of a rare tumour managed within a cooperative comprehensive project
AU - Sironi, Giovanna
AU - Ferrari, Andrea
AU - Podda, Marta
AU - Chiaravalli, Stefano
AU - Bisogno, Gianni
AU - Cecchetto, Giovanni
AU - Massimino, Maura
PY - 2016/11/1
Y1 - 2016/11/1
N2 - Though rare in childhood, thyroid cancers represent the most frequent tumours of endocrine glands in childhood and adolescence. Papillary thyroid carcinoma is a nonmedullary, follicular-derived differentiated tumour of the thyroid. There is still controversy concerning the therapeutic approach to be adopted of PTCs in the paediatric population, regarding the extent of the surgical approach, and the need for radioactive iodine (RAI) therapy. The cooperative TREP project (Tumori Rari in Età Pediatrica Rare Tumours in Paediatric Age]) was launched in Italy in 2000 (under the patronage of AIEOP Associazione Italiana Ematologia Oncologia Pediatrica) with a view to improving both researches on the clinical management of the less common paediatric cancers. The aim of the project is to merge clinical data and elaborate diagnostic and therapeutic guidelines for everyone of these rare tumours within a single framework: of course papillary thyroid carcinoma have been analysed in the TREP project. The cooperative model of TREP led to the establishment of a larger cooperative group, EXPeRT (European Cooperative Study Group for Pediatric Rare Tumors), seeking to create collaboration and communication within European members. EXPeRT aims to promote clinical and biological research in paediatric rare tumours by strengthening collaboration between the founder national groups and international partners. The studies have demonstrated that international cooperation in childhood rare tumours is not only achievable, but may be of great advantage.
AB - Though rare in childhood, thyroid cancers represent the most frequent tumours of endocrine glands in childhood and adolescence. Papillary thyroid carcinoma is a nonmedullary, follicular-derived differentiated tumour of the thyroid. There is still controversy concerning the therapeutic approach to be adopted of PTCs in the paediatric population, regarding the extent of the surgical approach, and the need for radioactive iodine (RAI) therapy. The cooperative TREP project (Tumori Rari in Età Pediatrica Rare Tumours in Paediatric Age]) was launched in Italy in 2000 (under the patronage of AIEOP Associazione Italiana Ematologia Oncologia Pediatrica) with a view to improving both researches on the clinical management of the less common paediatric cancers. The aim of the project is to merge clinical data and elaborate diagnostic and therapeutic guidelines for everyone of these rare tumours within a single framework: of course papillary thyroid carcinoma have been analysed in the TREP project. The cooperative model of TREP led to the establishment of a larger cooperative group, EXPeRT (European Cooperative Study Group for Pediatric Rare Tumors), seeking to create collaboration and communication within European members. EXPeRT aims to promote clinical and biological research in paediatric rare tumours by strengthening collaboration between the founder national groups and international partners. The studies have demonstrated that international cooperation in childhood rare tumours is not only achievable, but may be of great advantage.
KW - Children
KW - EXPeRT
KW - Rare tumours
KW - Thyroid carcinoma
KW - TREP
UR - http://www.scopus.com/inward/record.url?scp=85009279050&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85009279050&partnerID=8YFLogxK
U2 - 10.2174/1573396312666161031163319
DO - 10.2174/1573396312666161031163319
M3 - Review article
AN - SCOPUS:85009279050
VL - 12
SP - 265
EP - 271
JO - Population Research and Policy Review
JF - Population Research and Policy Review
SN - 0167-5923
IS - 4
ER -