Papillary thyroid carcinoma in three siblings with familial adenomatous polyposis

S. Civitelli, G. Tanzini, F. Cetta, M. Petracci, M. C. Pacchiarotti, B. Civitelli

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Abstract

The authors report three siblings (two sisters and their aunt, aged 20, 22 and 36, respectively) with familial adenomatous polyposis (FAP) and papillary thyroid carcinoma. After diagnosis of FAP, a single, non palpable nodule was revealed in each patient by routine screening ultrasonography of the gland. The diagnosis of papillary carcinoma was made by fine-needle-aspiration biopsy of the nodules and confirmed by histologic examination of surgical specimens. A review of the literature reveals about 40 reports of such an association, that is considered not fortuitous. Nevertheless, in this family the association seems to be a distinctive, clinical feature of the syndrome, affecting three out of five members intensively screened for extracolonic lesions.

Original languageEnglish
Pages (from-to)34-37
Number of pages4
JournalInternational Journal of Colorectal Disease
Volume11
Issue number1
DOIs
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Gastroenterology

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    Civitelli, S., Tanzini, G., Cetta, F., Petracci, M., Pacchiarotti, M. C., & Civitelli, B. (1996). Papillary thyroid carcinoma in three siblings with familial adenomatous polyposis. International Journal of Colorectal Disease, 11(1), 34-37. https://doi.org/10.1007/s003840050015