Paracervical anesthesia for outpatient hysteroscopy

P. Vercellini, A. Colombo, F. Mauro, S. Oldani, T. Bramante, P. G. Crosignani

Research output: Contribution to journalArticlepeer-review


One hundred seventy-seven women aged 41 ± 8 (mean ± SD) years, referred for evaluation of excessive uterine bleeding, were enrolled in an open-label randomized trial to evaluate the efficacy of local anesthesia before hysteroscopy in an outpatient population. The patients underwent hysteroscopy and endometrial biopsy with paracervical block by 10 mL of 1% mepivacaine hydrochloride solution (n = 87) or no local anesthesia (n = 90) and assessed lower abdominal and pelvic pain according to a 10-point linear analog scale. The mean ± SD pain score was 4.5 ± 2.0 at hysteroscopy and 5.2 ± 2.1 at endometrial biopsy in the 87 subjects given a paracervical block versus 4.9 ± 2.2 and 5.7 ± 2.4 in the 90 women not given local anesthesia, without statistically significant differences. Paracervical anesthesia for routine outpatient hysteroscopy in premenopausal women may be superfluous.

Original languageEnglish
Pages (from-to)1083-1085
Number of pages3
JournalFertility and Sterility
Issue number5
Publication statusPublished - 1994


  • endometrium
  • Hysteroscopy
  • local anesthesia
  • menorrhagia

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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