Parafollicular cells of rabbit thyroid store both calcitonin and somatostatin and resemble gut D cells ultrastructurally

R. Buffa, J. A. Chayvialle, P. Fontana, L. Usellini, C. Capella, E. Solcia

Research output: Contribution to journalArticlepeer-review

Abstract

Both calcitonin and somatostatin have been detected immunohistochemically in rabbit parafollicular cells; only calcitonin has been found in the same cells of the dog, guinea-pig and man. Large amounts of a peptide radioimmunochemically identical with synthetic somatostatin have been detected in extracts of rabbit thyroid. The ultrastructural and staining features of rabbit parafollicular cells differ from those of parafollicular cells in other species, while resembling in part those of somatostatin D cells scattered in the rabbit stomach.

Original languageEnglish
Pages (from-to)281-288
Number of pages8
JournalHistochemistry
Volume62
Issue number3
DOIs
Publication statusPublished - Jan 1979

ASJC Scopus subject areas

  • Anatomy

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