Parallel processing of sensory inputs: An evoked potentials study in Parkinsonian patients implanted with thalamic stimulators

Angelo Insola, Simone Rossi, Paolo Mazzone, Patrizio Pasqualetti

Research output: Contribution to journalArticle

Abstract

In two drug-resistant Parkinsonian subjects, who underwent thalamic chronic stimulation for extrapyramidal symptoms relief, median nerve somatosensory evoked potentials (SEPs) were recorded before and at different times following the thalamic lead implant. In both subjects, a transient obliteration of post-rolandic SEPs components was detected; pre-rolandic waves' amplitude was preserved or showed a tendency to increase after the beginning of chronic stimulation. Parietal waves' amplitude totally recovered pre-surgical values after 1 month. Latency of both pre- and post-central components remained stable. The 'dissociate behaviour' of the examined waves following the thalamic implant reinforces the hypothesis that short-latency sensory inputs are processed by separate and independent routes which are functionally segregated at subcortical level.

Original languageEnglish
Pages (from-to)146-151
Number of pages6
JournalClinical Neurophysiology
Volume110
Issue number1
DOIs
Publication statusPublished - Jan 1999

Keywords

  • Parkinson's disease
  • Somatosensory evoked potentials
  • Thalamic stimulation

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Sensory Systems
  • Physiology (medical)

Fingerprint Dive into the research topics of 'Parallel processing of sensory inputs: An evoked potentials study in Parkinsonian patients implanted with thalamic stimulators'. Together they form a unique fingerprint.

  • Cite this