Paranasal sinuses and middle ear infections: What do they have in common?

P. Marchisio, E. Ghisalberti, M. Fusi, E. Baggi, M. Ragazzi, E. Dusi

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Otitis media and sinusitis are among the most common pediatric diseases and they share common features. Although the anatomy, physiology and disease processes are not identical, knowledge of the pathophysiology of middle ear disorders often provides to the pediatrician a useful understanding of sinus diseases. The same risk factors identified for otitis media may play a pivotal role in the development of sinusitis. Moreover, as both paranasal sinuses and middle ear acquire respiratory pathogens from nasopharynx, acute sinusitis is usually caused by the same bacterial pathogens that cause acute otitis media, with a major role for Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis, while anaerobes may predominate in chronic disease. A responsibility of bacterial biofilms in chronic sinusitis, similarly to otitis media, has been recently suggested. Biofilms, three-dimensional aggregates of bacteria, are refractory to antibiotics and thus might explain why some patients improve while on antibiotics but relapse after completion of therapy.

Original languageEnglish
Pages (from-to)31-34
Number of pages4
JournalPediatric Allergy and Immunology
Volume18
Issue numberSUPPL. 18
DOIs
Publication statusPublished - Nov 2007

Fingerprint

Paranasal Sinuses
Sinusitis
Otitis Media
Middle Ear
Biofilms
Infection
Anti-Bacterial Agents
Moraxella (Branhamella) catarrhalis
Nasopharynx
Haemophilus influenzae
Streptococcus pneumoniae
Anatomy
Chronic Disease
Pediatrics
Bacteria
Recurrence
Therapeutics

Keywords

  • Microbiology
  • Otitis media
  • Sinusitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Pediatrics, Perinatology, and Child Health
  • Immunology

Cite this

Paranasal sinuses and middle ear infections : What do they have in common? / Marchisio, P.; Ghisalberti, E.; Fusi, M.; Baggi, E.; Ragazzi, M.; Dusi, E.

In: Pediatric Allergy and Immunology, Vol. 18, No. SUPPL. 18, 11.2007, p. 31-34.

Research output: Contribution to journalArticle

Marchisio, P. ; Ghisalberti, E. ; Fusi, M. ; Baggi, E. ; Ragazzi, M. ; Dusi, E. / Paranasal sinuses and middle ear infections : What do they have in common?. In: Pediatric Allergy and Immunology. 2007 ; Vol. 18, No. SUPPL. 18. pp. 31-34.
@article{aa3a40c47315484fb2ad1dfbb762299a,
title = "Paranasal sinuses and middle ear infections: What do they have in common?",
abstract = "Otitis media and sinusitis are among the most common pediatric diseases and they share common features. Although the anatomy, physiology and disease processes are not identical, knowledge of the pathophysiology of middle ear disorders often provides to the pediatrician a useful understanding of sinus diseases. The same risk factors identified for otitis media may play a pivotal role in the development of sinusitis. Moreover, as both paranasal sinuses and middle ear acquire respiratory pathogens from nasopharynx, acute sinusitis is usually caused by the same bacterial pathogens that cause acute otitis media, with a major role for Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis, while anaerobes may predominate in chronic disease. A responsibility of bacterial biofilms in chronic sinusitis, similarly to otitis media, has been recently suggested. Biofilms, three-dimensional aggregates of bacteria, are refractory to antibiotics and thus might explain why some patients improve while on antibiotics but relapse after completion of therapy.",
keywords = "Microbiology, Otitis media, Sinusitis",
author = "P. Marchisio and E. Ghisalberti and M. Fusi and E. Baggi and M. Ragazzi and E. Dusi",
year = "2007",
month = "11",
doi = "10.1111/j.1399-3038.2007.00630.x",
language = "English",
volume = "18",
pages = "31--34",
journal = "Pediatric Allergy and Immunology",
issn = "0905-6157",
publisher = "Blackwell Munksgaard",
number = "SUPPL. 18",

}

TY - JOUR

T1 - Paranasal sinuses and middle ear infections

T2 - What do they have in common?

AU - Marchisio, P.

AU - Ghisalberti, E.

AU - Fusi, M.

AU - Baggi, E.

AU - Ragazzi, M.

AU - Dusi, E.

PY - 2007/11

Y1 - 2007/11

N2 - Otitis media and sinusitis are among the most common pediatric diseases and they share common features. Although the anatomy, physiology and disease processes are not identical, knowledge of the pathophysiology of middle ear disorders often provides to the pediatrician a useful understanding of sinus diseases. The same risk factors identified for otitis media may play a pivotal role in the development of sinusitis. Moreover, as both paranasal sinuses and middle ear acquire respiratory pathogens from nasopharynx, acute sinusitis is usually caused by the same bacterial pathogens that cause acute otitis media, with a major role for Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis, while anaerobes may predominate in chronic disease. A responsibility of bacterial biofilms in chronic sinusitis, similarly to otitis media, has been recently suggested. Biofilms, three-dimensional aggregates of bacteria, are refractory to antibiotics and thus might explain why some patients improve while on antibiotics but relapse after completion of therapy.

AB - Otitis media and sinusitis are among the most common pediatric diseases and they share common features. Although the anatomy, physiology and disease processes are not identical, knowledge of the pathophysiology of middle ear disorders often provides to the pediatrician a useful understanding of sinus diseases. The same risk factors identified for otitis media may play a pivotal role in the development of sinusitis. Moreover, as both paranasal sinuses and middle ear acquire respiratory pathogens from nasopharynx, acute sinusitis is usually caused by the same bacterial pathogens that cause acute otitis media, with a major role for Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis, while anaerobes may predominate in chronic disease. A responsibility of bacterial biofilms in chronic sinusitis, similarly to otitis media, has been recently suggested. Biofilms, three-dimensional aggregates of bacteria, are refractory to antibiotics and thus might explain why some patients improve while on antibiotics but relapse after completion of therapy.

KW - Microbiology

KW - Otitis media

KW - Sinusitis

UR - http://www.scopus.com/inward/record.url?scp=34548307252&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34548307252&partnerID=8YFLogxK

U2 - 10.1111/j.1399-3038.2007.00630.x

DO - 10.1111/j.1399-3038.2007.00630.x

M3 - Article

C2 - 17767605

AN - SCOPUS:34548307252

VL - 18

SP - 31

EP - 34

JO - Pediatric Allergy and Immunology

JF - Pediatric Allergy and Immunology

SN - 0905-6157

IS - SUPPL. 18

ER -