TY - JOUR
T1 - Paraneoplastic cerebellar degeneration associated with ovarian cancer
AU - Russo, Alessia Erika
AU - Scalone, Simona
AU - Leonardi, Giulia Costanza
AU - Scalisi, Aurora
AU - Giorda, Giorgio
AU - Sorio, Roberto
PY - 2013/2
Y1 - 2013/2
N2 - Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction. PCD often precedes the cancer diagnosis by months to years. Here, we report the case of a 64-year-old woman who developed PCD symptoms, associated with high levels of anti-Yo antibodies, one year after a previous diagnosis of ovarian cancer. Clinical features, pathogenesis and treatment of PCD associated with cancer are discussed according to previous studies.
AB - Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction. PCD often precedes the cancer diagnosis by months to years. Here, we report the case of a 64-year-old woman who developed PCD symptoms, associated with high levels of anti-Yo antibodies, one year after a previous diagnosis of ovarian cancer. Clinical features, pathogenesis and treatment of PCD associated with cancer are discussed according to previous studies.
KW - Anti-Yo
KW - Ovarian cancer
KW - Paraneoplastic cerebellar degeneration
UR - http://www.scopus.com/inward/record.url?scp=84871600186&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84871600186&partnerID=8YFLogxK
U2 - 10.3892/ol.2012.1016
DO - 10.3892/ol.2012.1016
M3 - Article
AN - SCOPUS:84871600186
VL - 5
SP - 681
EP - 683
JO - Oncology Letters
JF - Oncology Letters
SN - 1792-1074
IS - 2
ER -