Paraneoplastic cerebellar degeneration associated with ovarian cancer

Alessia Erika Russo, Simona Scalone, Giulia Costanza Leonardi, Aurora Scalisi, Giorgio Giorda, Roberto Sorio

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction. PCD often precedes the cancer diagnosis by months to years. Here, we report the case of a 64-year-old woman who developed PCD symptoms, associated with high levels of anti-Yo antibodies, one year after a previous diagnosis of ovarian cancer. Clinical features, pathogenesis and treatment of PCD associated with cancer are discussed according to previous studies.

Original languageEnglish
Pages (from-to)681-683
Number of pages3
JournalOncology Letters
Volume5
Issue number2
DOIs
Publication statusPublished - Feb 2013

Fingerprint

Paraneoplastic Cerebellar Degeneration
Ovarian Neoplasms
Purkinje Cells
Nervous System Diseases
Anti-Idiotypic Antibodies
Neoplasms

Keywords

  • Anti-Yo
  • Ovarian cancer
  • Paraneoplastic cerebellar degeneration

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Paraneoplastic cerebellar degeneration associated with ovarian cancer. / Russo, Alessia Erika; Scalone, Simona; Leonardi, Giulia Costanza; Scalisi, Aurora; Giorda, Giorgio; Sorio, Roberto.

In: Oncology Letters, Vol. 5, No. 2, 02.2013, p. 681-683.

Research output: Contribution to journalArticle

Russo, Alessia Erika ; Scalone, Simona ; Leonardi, Giulia Costanza ; Scalisi, Aurora ; Giorda, Giorgio ; Sorio, Roberto. / Paraneoplastic cerebellar degeneration associated with ovarian cancer. In: Oncology Letters. 2013 ; Vol. 5, No. 2. pp. 681-683.
@article{32a68231439e446b95541c14cd30f0d0,
title = "Paraneoplastic cerebellar degeneration associated with ovarian cancer",
abstract = "Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction. PCD often precedes the cancer diagnosis by months to years. Here, we report the case of a 64-year-old woman who developed PCD symptoms, associated with high levels of anti-Yo antibodies, one year after a previous diagnosis of ovarian cancer. Clinical features, pathogenesis and treatment of PCD associated with cancer are discussed according to previous studies.",
keywords = "Anti-Yo, Ovarian cancer, Paraneoplastic cerebellar degeneration",
author = "Russo, {Alessia Erika} and Simona Scalone and Leonardi, {Giulia Costanza} and Aurora Scalisi and Giorgio Giorda and Roberto Sorio",
year = "2013",
month = "2",
doi = "10.3892/ol.2012.1016",
language = "English",
volume = "5",
pages = "681--683",
journal = "Oncology Letters",
issn = "1792-1074",
publisher = "Spandidos Publications",
number = "2",

}

TY - JOUR

T1 - Paraneoplastic cerebellar degeneration associated with ovarian cancer

AU - Russo, Alessia Erika

AU - Scalone, Simona

AU - Leonardi, Giulia Costanza

AU - Scalisi, Aurora

AU - Giorda, Giorgio

AU - Sorio, Roberto

PY - 2013/2

Y1 - 2013/2

N2 - Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction. PCD often precedes the cancer diagnosis by months to years. Here, we report the case of a 64-year-old woman who developed PCD symptoms, associated with high levels of anti-Yo antibodies, one year after a previous diagnosis of ovarian cancer. Clinical features, pathogenesis and treatment of PCD associated with cancer are discussed according to previous studies.

AB - Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction. PCD often precedes the cancer diagnosis by months to years. Here, we report the case of a 64-year-old woman who developed PCD symptoms, associated with high levels of anti-Yo antibodies, one year after a previous diagnosis of ovarian cancer. Clinical features, pathogenesis and treatment of PCD associated with cancer are discussed according to previous studies.

KW - Anti-Yo

KW - Ovarian cancer

KW - Paraneoplastic cerebellar degeneration

UR - http://www.scopus.com/inward/record.url?scp=84871600186&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84871600186&partnerID=8YFLogxK

U2 - 10.3892/ol.2012.1016

DO - 10.3892/ol.2012.1016

M3 - Article

AN - SCOPUS:84871600186

VL - 5

SP - 681

EP - 683

JO - Oncology Letters

JF - Oncology Letters

SN - 1792-1074

IS - 2

ER -