Paraneoplastic cerebellar degeneration associated with ovarian cancer

Alessia Erika Russo, Simona Scalone, Giulia Costanza Leonardi, Aurora Scalisi, Giorgio Giorda, Roberto Sorio

Research output: Contribution to journalArticlepeer-review


Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction. PCD often precedes the cancer diagnosis by months to years. Here, we report the case of a 64-year-old woman who developed PCD symptoms, associated with high levels of anti-Yo antibodies, one year after a previous diagnosis of ovarian cancer. Clinical features, pathogenesis and treatment of PCD associated with cancer are discussed according to previous studies.

Original languageEnglish
Pages (from-to)681-683
Number of pages3
JournalOncology Letters
Issue number2
Publication statusPublished - Feb 2013


  • Anti-Yo
  • Ovarian cancer
  • Paraneoplastic cerebellar degeneration

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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