Paraneoplastic remitting seronegative symmetrical synovitis with pitting edema

F. Cantini, C. Salvarani, I. Olivieri

Research output: Contribution to journalArticle


Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a syndrome that may be associated with many conditions, including malignancy. Three further cases of paraneoplastic RS3PE are described and the literature is reviewed. Paraneoplastic RS3PE is more frequently associated with solid tumors, in particular adenocarcinoma. The two clinical characteristics suggestive of paraneoplastic RS3PE are systemic sign/symptoms and the poor response to corticosteroid therapy.

Original languageEnglish
Pages (from-to)741-744
Number of pages4
JournalClinical and Experimental Rheumatology
Issue number6
Publication statusPublished - 1999



  • Malignancy
  • Paraneoplastic syndrome
  • RS3PE
  • Tenosynovitis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

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