Abstract
Background: The purpose of this study was to present a case of paraneoplastic systemic hypertension and fever in an undiagnosed primary ciliary body carcinoma arising in a painful blind eye. Case presentation: A 37-year-old white man with a history of blindness since childhood was enucleated for neovascular glaucoma because of intractable pain in his right eye. A histopathological examination revealed a ciliary body carcinoma. One year later, an invasive recurrence of his orbit and ethmoid was detected and a debulking procedure was performed. He had untreatable fever and multidrug-resistant systemic hypertension for 3 months before the neoplasm diagnosis. He recovered from fever and systemic hypertension only after tumor excision and relapsed 1 year later when synchronous tumor dissemination was shown through a computed tomography scan. Tumor metastases, despite surgery and chemotherapy, caused his death. Conclusions: Paraneoplastic symptoms such as fever and hypertension may be due to unrecognized ocular malignancy. This case report intends to emphasize the importance of histopathological examination of an enucleated phthisical painful blind eye.
| Original language | English |
|---|---|
| Journal | Journal of Medical Case Reports |
| DOIs | |
| Publication status | Accepted/In press - Jan 18 2016 |
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Keywords
- Cancer
- Ciliary body carcinoma
- Systemic hypertension
ASJC Scopus subject areas
- Medicine(all)
Cite this
Paraneoplastic syndrome - unresponsive systemic hypertension and fever as expression of primitive ciliary body carcinoma in a blind painful eye : A case report. / Balia, Laura; Vinciguerra, Paolo; Di Maria, Alessandra; Piscopo, Raffaele; Romano, Mary.
In: Journal of Medical Case Reports, 18.01.2016.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Paraneoplastic syndrome - unresponsive systemic hypertension and fever as expression of primitive ciliary body carcinoma in a blind painful eye
T2 - A case report
AU - Balia, Laura
AU - Vinciguerra, Paolo
AU - Di Maria, Alessandra
AU - Piscopo, Raffaele
AU - Romano, Mary
PY - 2016/1/18
Y1 - 2016/1/18
N2 - Background: The purpose of this study was to present a case of paraneoplastic systemic hypertension and fever in an undiagnosed primary ciliary body carcinoma arising in a painful blind eye. Case presentation: A 37-year-old white man with a history of blindness since childhood was enucleated for neovascular glaucoma because of intractable pain in his right eye. A histopathological examination revealed a ciliary body carcinoma. One year later, an invasive recurrence of his orbit and ethmoid was detected and a debulking procedure was performed. He had untreatable fever and multidrug-resistant systemic hypertension for 3 months before the neoplasm diagnosis. He recovered from fever and systemic hypertension only after tumor excision and relapsed 1 year later when synchronous tumor dissemination was shown through a computed tomography scan. Tumor metastases, despite surgery and chemotherapy, caused his death. Conclusions: Paraneoplastic symptoms such as fever and hypertension may be due to unrecognized ocular malignancy. This case report intends to emphasize the importance of histopathological examination of an enucleated phthisical painful blind eye.
AB - Background: The purpose of this study was to present a case of paraneoplastic systemic hypertension and fever in an undiagnosed primary ciliary body carcinoma arising in a painful blind eye. Case presentation: A 37-year-old white man with a history of blindness since childhood was enucleated for neovascular glaucoma because of intractable pain in his right eye. A histopathological examination revealed a ciliary body carcinoma. One year later, an invasive recurrence of his orbit and ethmoid was detected and a debulking procedure was performed. He had untreatable fever and multidrug-resistant systemic hypertension for 3 months before the neoplasm diagnosis. He recovered from fever and systemic hypertension only after tumor excision and relapsed 1 year later when synchronous tumor dissemination was shown through a computed tomography scan. Tumor metastases, despite surgery and chemotherapy, caused his death. Conclusions: Paraneoplastic symptoms such as fever and hypertension may be due to unrecognized ocular malignancy. This case report intends to emphasize the importance of histopathological examination of an enucleated phthisical painful blind eye.
KW - Cancer
KW - Ciliary body carcinoma
KW - Systemic hypertension
UR - http://www.scopus.com/inward/record.url?scp=84954341823&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84954341823&partnerID=8YFLogxK
U2 - 10.1186/s13256-015-0782-6
DO - 10.1186/s13256-015-0782-6
M3 - Article
JO - Journal of Medical Case Reports
JF - Journal of Medical Case Reports
SN - 1752-1947
ER -