Parasitic infections on the shore of Lake Victoria (East Africa) detected by Mini-FLOTAC and standard techniques

Beatrice Barda, Davide Ianniello, Henry Zepheryne, Laura Rinaldi, Giuseppe Cringoli, Roberto Burioni, Marco Albonico

Research output: Contribution to journalArticle

Abstract

Background: Helminths and protozoa infections pose a great burden especially in developing countries, due to morbidity caused by both acute and chronic infection. The aim of our survey was to analyze the intestinal parasitic burden in communities from Mwanza region, Tanzania. Methods: Subjects (n= 251) from four villages on the South of Lake Victoria have been analyzed for intestinal parasites with direct smear (DS), formol-ether concentration method (FECM) and the newly developed Mini-FLOTAC technique; urinary schistosomiasis was also assessed in a subsample (n= 151); symptoms were registered and correlation between clinic and infections was calculated by chi-squared test and logistical regression. Results: Out of the subjects screened for intestinal and for urinary parasites, 87% (218/251) were found positive for any infection, 69% (174/251) carried a helminthic and 67% (167/251) a protozoan infection, almost half of them had a double or triple infection. The most common helminths were hookworms, followed by Schistosoma mansoni and Schistosoma haematobium. Among protozoa, the most common was Entamoeba coli followed by Entamoeba histolytica/dispar and Giardia intestinalis. Mini-FLOTAC detected a number of helminth infections (61.7%) higher than FECM (38.6%) and DS (17.9%). Some positive associations with abdominal symptoms were found and previous treatment was negatively correlated with infection. Conclusion: Despite the limited size of the examined population the current study indicates a high prevalence of intestinal parasitic infection in Bukumbi area, Tanzania, and Mini-FLOTAC showed to be a promising diagnostic tool for helminth infections. This high parasitic burden calls for starting a regular deworming programme and other preventive interventions in schools and in the community.

Original languageEnglish
Pages (from-to)140-146
Number of pages7
JournalActa Tropica
Volume137
DOIs
Publication statusPublished - 2014

Fingerprint

Eastern Africa
Lake Victoria
Parasitic Diseases
Victoria
parasitoses
Lakes
Helminths
Infection
infection
helminthiasis
Tanzania
formalin
helminths
signs and symptoms (animals and humans)
Protozoa
ethers
methodology
Ether
Schistosoma haematobium
Formaldehyde

Keywords

  • Helminths
  • Intestinal parasitic infections
  • Protozoa
  • Tanzania

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Medicine(all)

Cite this

Parasitic infections on the shore of Lake Victoria (East Africa) detected by Mini-FLOTAC and standard techniques. / Barda, Beatrice; Ianniello, Davide; Zepheryne, Henry; Rinaldi, Laura; Cringoli, Giuseppe; Burioni, Roberto; Albonico, Marco.

In: Acta Tropica, Vol. 137, 2014, p. 140-146.

Research output: Contribution to journalArticle

Barda, Beatrice ; Ianniello, Davide ; Zepheryne, Henry ; Rinaldi, Laura ; Cringoli, Giuseppe ; Burioni, Roberto ; Albonico, Marco. / Parasitic infections on the shore of Lake Victoria (East Africa) detected by Mini-FLOTAC and standard techniques. In: Acta Tropica. 2014 ; Vol. 137. pp. 140-146.
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abstract = "Background: Helminths and protozoa infections pose a great burden especially in developing countries, due to morbidity caused by both acute and chronic infection. The aim of our survey was to analyze the intestinal parasitic burden in communities from Mwanza region, Tanzania. Methods: Subjects (n= 251) from four villages on the South of Lake Victoria have been analyzed for intestinal parasites with direct smear (DS), formol-ether concentration method (FECM) and the newly developed Mini-FLOTAC technique; urinary schistosomiasis was also assessed in a subsample (n= 151); symptoms were registered and correlation between clinic and infections was calculated by chi-squared test and logistical regression. Results: Out of the subjects screened for intestinal and for urinary parasites, 87{\%} (218/251) were found positive for any infection, 69{\%} (174/251) carried a helminthic and 67{\%} (167/251) a protozoan infection, almost half of them had a double or triple infection. The most common helminths were hookworms, followed by Schistosoma mansoni and Schistosoma haematobium. Among protozoa, the most common was Entamoeba coli followed by Entamoeba histolytica/dispar and Giardia intestinalis. Mini-FLOTAC detected a number of helminth infections (61.7{\%}) higher than FECM (38.6{\%}) and DS (17.9{\%}). Some positive associations with abdominal symptoms were found and previous treatment was negatively correlated with infection. Conclusion: Despite the limited size of the examined population the current study indicates a high prevalence of intestinal parasitic infection in Bukumbi area, Tanzania, and Mini-FLOTAC showed to be a promising diagnostic tool for helminth infections. This high parasitic burden calls for starting a regular deworming programme and other preventive interventions in schools and in the community.",
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AU - Barda, Beatrice

AU - Ianniello, Davide

AU - Zepheryne, Henry

AU - Rinaldi, Laura

AU - Cringoli, Giuseppe

AU - Burioni, Roberto

AU - Albonico, Marco

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AB - Background: Helminths and protozoa infections pose a great burden especially in developing countries, due to morbidity caused by both acute and chronic infection. The aim of our survey was to analyze the intestinal parasitic burden in communities from Mwanza region, Tanzania. Methods: Subjects (n= 251) from four villages on the South of Lake Victoria have been analyzed for intestinal parasites with direct smear (DS), formol-ether concentration method (FECM) and the newly developed Mini-FLOTAC technique; urinary schistosomiasis was also assessed in a subsample (n= 151); symptoms were registered and correlation between clinic and infections was calculated by chi-squared test and logistical regression. Results: Out of the subjects screened for intestinal and for urinary parasites, 87% (218/251) were found positive for any infection, 69% (174/251) carried a helminthic and 67% (167/251) a protozoan infection, almost half of them had a double or triple infection. The most common helminths were hookworms, followed by Schistosoma mansoni and Schistosoma haematobium. Among protozoa, the most common was Entamoeba coli followed by Entamoeba histolytica/dispar and Giardia intestinalis. Mini-FLOTAC detected a number of helminth infections (61.7%) higher than FECM (38.6%) and DS (17.9%). Some positive associations with abdominal symptoms were found and previous treatment was negatively correlated with infection. Conclusion: Despite the limited size of the examined population the current study indicates a high prevalence of intestinal parasitic infection in Bukumbi area, Tanzania, and Mini-FLOTAC showed to be a promising diagnostic tool for helminth infections. This high parasitic burden calls for starting a regular deworming programme and other preventive interventions in schools and in the community.

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