Parenchyma-sparing resections for pancreatic neoplasms

Stefano Crippa, Letizia Boninsegna, Stefano Partelli, Massimo Falconi

Research output: Contribution to journalArticle

Abstract

Background/purpose: In recent years there has been an increase in the indications for pancreatic resection of benign or low-grade malignant lesions, especially in young patients with long life expectancy. In this setting, patients may benefit from parenchyma-sparing resections in order to decrease the risk of development of exocrine/endocrine insufficiency. Methods: A review of the literature and authors experience was undertaken. Results: Parenchyma-sparing resections of the pancreas including enucleation, middle pancreatectomy (MP) and middle-preserving pancreatectomy are described. Short and long-term outcomes after surgery are analyzed with special regard to postoperative morbidity/mortality, and oncological and functional long-term results. Conclusions: Parenchyma-sparing resections are safe and effective procedures for treatment of benign and low-grade malignant neoplasms. Despite a significant postoperative morbidity they are associated with good long-term functional and oncological results. Enucleation should preferentially be performed laparoscopically whenever possible.

Original languageEnglish
Pages (from-to)782-787
Number of pages6
JournalJournal of Hepato-Biliary-Pancreatic Sciences
Volume17
Issue number6
DOIs
Publication statusPublished - Nov 2010

Fingerprint

Pancreatectomy
Pancreatic Neoplasms
Morbidity
Life Expectancy
Pancreas
Mortality
Neoplasms
Therapeutics

Keywords

  • Endocrine tumor
  • Enucleation
  • Intraductal papillary mucinous tumor
  • Middle pancreatectomy
  • Parenchyma-sparing
  • Recurrence
  • Resections

ASJC Scopus subject areas

  • Hepatology
  • Surgery
  • Medicine(all)

Cite this

Parenchyma-sparing resections for pancreatic neoplasms. / Crippa, Stefano; Boninsegna, Letizia; Partelli, Stefano; Falconi, Massimo.

In: Journal of Hepato-Biliary-Pancreatic Sciences, Vol. 17, No. 6, 11.2010, p. 782-787.

Research output: Contribution to journalArticle

Crippa, Stefano ; Boninsegna, Letizia ; Partelli, Stefano ; Falconi, Massimo. / Parenchyma-sparing resections for pancreatic neoplasms. In: Journal of Hepato-Biliary-Pancreatic Sciences. 2010 ; Vol. 17, No. 6. pp. 782-787.
@article{ea716405b8d14fa3bed5190ee662f9ba,
title = "Parenchyma-sparing resections for pancreatic neoplasms",
abstract = "Background/purpose: In recent years there has been an increase in the indications for pancreatic resection of benign or low-grade malignant lesions, especially in young patients with long life expectancy. In this setting, patients may benefit from parenchyma-sparing resections in order to decrease the risk of development of exocrine/endocrine insufficiency. Methods: A review of the literature and authors experience was undertaken. Results: Parenchyma-sparing resections of the pancreas including enucleation, middle pancreatectomy (MP) and middle-preserving pancreatectomy are described. Short and long-term outcomes after surgery are analyzed with special regard to postoperative morbidity/mortality, and oncological and functional long-term results. Conclusions: Parenchyma-sparing resections are safe and effective procedures for treatment of benign and low-grade malignant neoplasms. Despite a significant postoperative morbidity they are associated with good long-term functional and oncological results. Enucleation should preferentially be performed laparoscopically whenever possible.",
keywords = "Endocrine tumor, Enucleation, Intraductal papillary mucinous tumor, Middle pancreatectomy, Parenchyma-sparing, Recurrence, Resections",
author = "Stefano Crippa and Letizia Boninsegna and Stefano Partelli and Massimo Falconi",
year = "2010",
month = "11",
doi = "10.1007/s00534-009-0224-1",
language = "English",
volume = "17",
pages = "782--787",
journal = "Journal of Hepato-Biliary-Pancreatic Sciences",
issn = "1868-6974",
publisher = "Springer Verlag",
number = "6",

}

TY - JOUR

T1 - Parenchyma-sparing resections for pancreatic neoplasms

AU - Crippa, Stefano

AU - Boninsegna, Letizia

AU - Partelli, Stefano

AU - Falconi, Massimo

PY - 2010/11

Y1 - 2010/11

N2 - Background/purpose: In recent years there has been an increase in the indications for pancreatic resection of benign or low-grade malignant lesions, especially in young patients with long life expectancy. In this setting, patients may benefit from parenchyma-sparing resections in order to decrease the risk of development of exocrine/endocrine insufficiency. Methods: A review of the literature and authors experience was undertaken. Results: Parenchyma-sparing resections of the pancreas including enucleation, middle pancreatectomy (MP) and middle-preserving pancreatectomy are described. Short and long-term outcomes after surgery are analyzed with special regard to postoperative morbidity/mortality, and oncological and functional long-term results. Conclusions: Parenchyma-sparing resections are safe and effective procedures for treatment of benign and low-grade malignant neoplasms. Despite a significant postoperative morbidity they are associated with good long-term functional and oncological results. Enucleation should preferentially be performed laparoscopically whenever possible.

AB - Background/purpose: In recent years there has been an increase in the indications for pancreatic resection of benign or low-grade malignant lesions, especially in young patients with long life expectancy. In this setting, patients may benefit from parenchyma-sparing resections in order to decrease the risk of development of exocrine/endocrine insufficiency. Methods: A review of the literature and authors experience was undertaken. Results: Parenchyma-sparing resections of the pancreas including enucleation, middle pancreatectomy (MP) and middle-preserving pancreatectomy are described. Short and long-term outcomes after surgery are analyzed with special regard to postoperative morbidity/mortality, and oncological and functional long-term results. Conclusions: Parenchyma-sparing resections are safe and effective procedures for treatment of benign and low-grade malignant neoplasms. Despite a significant postoperative morbidity they are associated with good long-term functional and oncological results. Enucleation should preferentially be performed laparoscopically whenever possible.

KW - Endocrine tumor

KW - Enucleation

KW - Intraductal papillary mucinous tumor

KW - Middle pancreatectomy

KW - Parenchyma-sparing

KW - Recurrence

KW - Resections

UR - http://www.scopus.com/inward/record.url?scp=79952196911&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79952196911&partnerID=8YFLogxK

U2 - 10.1007/s00534-009-0224-1

DO - 10.1007/s00534-009-0224-1

M3 - Article

C2 - 19865792

AN - SCOPUS:79952196911

VL - 17

SP - 782

EP - 787

JO - Journal of Hepato-Biliary-Pancreatic Sciences

JF - Journal of Hepato-Biliary-Pancreatic Sciences

SN - 1868-6974

IS - 6

ER -