Parietal generators of low- and high-frequency MN (median nerve) SEPs: Data from intracortical human recordings

C. Barba, M. Valeriani, G. Colicchio, P. Tonali, D. Restuccia

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objective: To identify low and high-frequency median nerve (MN) somatosensory evoked potential (SEP) generators by means of chronically implanted electrodes in the parietal lobe (SI and neighbouring areas) of two epileptic patients. Methods: Wide-pass short-latency and long-latency SEPs to electrical MN stimulation were recorded in two epileptic patients by stereotactically chronically implanted electrodes in the parietal lobe (SI and neighbouring areas). To study high-frequency responses (HFOs) an off-line digital filtering of depth short-latency SEPs was performed (500-800 Hz, 24 dB roll-off). Spectral analysis was performed by fast Fourier transform. Results: In both patients we recorded a N20/P30 potential followed by a biphasic N50/P70 response. A little negative response in the 100 ms latency range was the last detectable wide-pass SEP in both patients. Two HFOs components (called iP1 and iP2) were detected by mere visual analysis and spectral analysis, and were supposed to be originated within the parietal cortex. Conclusions: This was the very first study that recorded wide bandpass and high frequency SEPs by electrodes, exploring both the lateral and the mesial part of the parietal lobe and particularly that of the post-central gyrus.

Original languageEnglish
Pages (from-to)647-657
Number of pages11
JournalClinical Neurophysiology
Volume115
Issue number3
DOIs
Publication statusPublished - Mar 2004

Fingerprint

Parietal Lobe
Median Nerve
Implanted Electrodes
Somatosensory Evoked Potentials
Somatosensory Cortex
Fourier Analysis
Electrodes

Keywords

  • Epilepsy investigations
  • Epilepsy surgery
  • High-frequency evoked responses
  • Intracortical potentials
  • SI area
  • Somatosensory evoked potentials

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Sensory Systems
  • Physiology (medical)

Cite this

Parietal generators of low- and high-frequency MN (median nerve) SEPs : Data from intracortical human recordings. / Barba, C.; Valeriani, M.; Colicchio, G.; Tonali, P.; Restuccia, D.

In: Clinical Neurophysiology, Vol. 115, No. 3, 03.2004, p. 647-657.

Research output: Contribution to journalArticle

@article{abd47be2648a494ea055e7b59e57e661,
title = "Parietal generators of low- and high-frequency MN (median nerve) SEPs: Data from intracortical human recordings",
abstract = "Objective: To identify low and high-frequency median nerve (MN) somatosensory evoked potential (SEP) generators by means of chronically implanted electrodes in the parietal lobe (SI and neighbouring areas) of two epileptic patients. Methods: Wide-pass short-latency and long-latency SEPs to electrical MN stimulation were recorded in two epileptic patients by stereotactically chronically implanted electrodes in the parietal lobe (SI and neighbouring areas). To study high-frequency responses (HFOs) an off-line digital filtering of depth short-latency SEPs was performed (500-800 Hz, 24 dB roll-off). Spectral analysis was performed by fast Fourier transform. Results: In both patients we recorded a N20/P30 potential followed by a biphasic N50/P70 response. A little negative response in the 100 ms latency range was the last detectable wide-pass SEP in both patients. Two HFOs components (called iP1 and iP2) were detected by mere visual analysis and spectral analysis, and were supposed to be originated within the parietal cortex. Conclusions: This was the very first study that recorded wide bandpass and high frequency SEPs by electrodes, exploring both the lateral and the mesial part of the parietal lobe and particularly that of the post-central gyrus.",
keywords = "Epilepsy investigations, Epilepsy surgery, High-frequency evoked responses, Intracortical potentials, SI area, Somatosensory evoked potentials",
author = "C. Barba and M. Valeriani and G. Colicchio and P. Tonali and D. Restuccia",
year = "2004",
month = "3",
doi = "10.1016/j.clinph.2003.10.024",
language = "English",
volume = "115",
pages = "647--657",
journal = "Clinical Neurophysiology",
issn = "1388-2457",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

TY - JOUR

T1 - Parietal generators of low- and high-frequency MN (median nerve) SEPs

T2 - Data from intracortical human recordings

AU - Barba, C.

AU - Valeriani, M.

AU - Colicchio, G.

AU - Tonali, P.

AU - Restuccia, D.

PY - 2004/3

Y1 - 2004/3

N2 - Objective: To identify low and high-frequency median nerve (MN) somatosensory evoked potential (SEP) generators by means of chronically implanted electrodes in the parietal lobe (SI and neighbouring areas) of two epileptic patients. Methods: Wide-pass short-latency and long-latency SEPs to electrical MN stimulation were recorded in two epileptic patients by stereotactically chronically implanted electrodes in the parietal lobe (SI and neighbouring areas). To study high-frequency responses (HFOs) an off-line digital filtering of depth short-latency SEPs was performed (500-800 Hz, 24 dB roll-off). Spectral analysis was performed by fast Fourier transform. Results: In both patients we recorded a N20/P30 potential followed by a biphasic N50/P70 response. A little negative response in the 100 ms latency range was the last detectable wide-pass SEP in both patients. Two HFOs components (called iP1 and iP2) were detected by mere visual analysis and spectral analysis, and were supposed to be originated within the parietal cortex. Conclusions: This was the very first study that recorded wide bandpass and high frequency SEPs by electrodes, exploring both the lateral and the mesial part of the parietal lobe and particularly that of the post-central gyrus.

AB - Objective: To identify low and high-frequency median nerve (MN) somatosensory evoked potential (SEP) generators by means of chronically implanted electrodes in the parietal lobe (SI and neighbouring areas) of two epileptic patients. Methods: Wide-pass short-latency and long-latency SEPs to electrical MN stimulation were recorded in two epileptic patients by stereotactically chronically implanted electrodes in the parietal lobe (SI and neighbouring areas). To study high-frequency responses (HFOs) an off-line digital filtering of depth short-latency SEPs was performed (500-800 Hz, 24 dB roll-off). Spectral analysis was performed by fast Fourier transform. Results: In both patients we recorded a N20/P30 potential followed by a biphasic N50/P70 response. A little negative response in the 100 ms latency range was the last detectable wide-pass SEP in both patients. Two HFOs components (called iP1 and iP2) were detected by mere visual analysis and spectral analysis, and were supposed to be originated within the parietal cortex. Conclusions: This was the very first study that recorded wide bandpass and high frequency SEPs by electrodes, exploring both the lateral and the mesial part of the parietal lobe and particularly that of the post-central gyrus.

KW - Epilepsy investigations

KW - Epilepsy surgery

KW - High-frequency evoked responses

KW - Intracortical potentials

KW - SI area

KW - Somatosensory evoked potentials

UR - http://www.scopus.com/inward/record.url?scp=1242292267&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1242292267&partnerID=8YFLogxK

U2 - 10.1016/j.clinph.2003.10.024

DO - 10.1016/j.clinph.2003.10.024

M3 - Article

C2 - 15036061

AN - SCOPUS:1242292267

VL - 115

SP - 647

EP - 657

JO - Clinical Neurophysiology

JF - Clinical Neurophysiology

SN - 1388-2457

IS - 3

ER -