Parkinson's disease: The non-motor issues

K. Ray Chaudhuri, Per Odin, Angelo Antonini, Pablo Martinez-Martin

Research output: Contribution to journalArticle

Abstract

Non-motor symptoms (NMS) of Parkinson's disease remain the most under-appreciated and under-researched when taken as a whole. Data is emerging that it is the "totaL" burden of NMS that is the major determinant of quality of life not a single NMS such as depression for instance. Only recently validated tools such as the NMSQuest which empowers patients to declare NMS and the NMS scale, the SCOPA scales, and the modified version of the MDS-UPDRS have become available and validated for bedside clinical assessment of NMS. For the first time clinical trials have been incorporating non-motor measures as outcome measures and clinical recommendations for treatment of non-motor symptoms of PD are being published. This review aims to address some of these topical and "real life" aspects of modern day management of Parkinson's.

Original languageEnglish
Pages (from-to)717-723
Number of pages7
JournalParkinsonism and Related Disorders
Volume17
Issue number10
DOIs
Publication statusPublished - Dec 2011

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Keywords

  • NMSQuest
  • Non-motor off period
  • Non-motor symptoms
  • Parkinson's disease

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Clinical Neurology
  • Neurology

Cite this

Chaudhuri, K. R., Odin, P., Antonini, A., & Martinez-Martin, P. (2011). Parkinson's disease: The non-motor issues. Parkinsonism and Related Disorders, 17(10), 717-723. https://doi.org/10.1016/j.parkreldis.2011.02.018