Parotid Gland Cancer

A Case Report of a Primitive Adenocarcinoma Arising from a Multirecurrent Pleomorphic Adenoma

Luciano Izzo, R. Frati, F. Cianfrone, P. G. Sassayannis, U. Costi, G. Galati, L. Lo Mele, Z. Kharrub, M. Marini, M. Caputo

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Parotid tumours represent a wide group of tumours which are mostly localized in the major salivary glands. We report a case of a 69-year old female with a parotid tumour history who was referred to us with a prominent lump and swelling localized in the right parotid area. In the period between 1985-2002, she was operated 5 times elsewhere for a recurrent pleomorphic adenoma of the right parotid (mixed tumour until 1991), which was histologically confirmed. Sixteen years after the primitive tumour, she underwent mastectomy and axillary dissection for a ductal carcinoma. Routine follow-up has been conducted on both malignancies. Pleomorphic adenoma is the most frequent tumour of the parotid. The potential risk of a malignant transformation can increase over the years with an incidence of 1% to 7%. Management of these recurrences is complex and controversial because of the different treatment options advocated such as radical resection with possible facial nerve sacrifice, or post-operative radiotherapy in non radical cases.

Original languageEnglish
Pages (from-to)153-156
Number of pages4
JournalJournal of Experimental and Clinical Cancer Research
Volume23
Issue number1
Publication statusPublished - Mar 2004

Fingerprint

Parotid Neoplasms
Pleomorphic Adenoma
Parotid Gland
Adenocarcinoma
Neoplasms
Ductal Carcinoma
Mastectomy
Facial Nerve
Salivary Glands
Dissection
Radiotherapy
Recurrence

Keywords

  • Adenocarcinoma
  • Parotid cancer
  • Pleomorphic adenoma
  • Recurrent tumour

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Parotid Gland Cancer : A Case Report of a Primitive Adenocarcinoma Arising from a Multirecurrent Pleomorphic Adenoma. / Izzo, Luciano; Frati, R.; Cianfrone, F.; Sassayannis, P. G.; Costi, U.; Galati, G.; Lo Mele, L.; Kharrub, Z.; Marini, M.; Caputo, M.

In: Journal of Experimental and Clinical Cancer Research, Vol. 23, No. 1, 03.2004, p. 153-156.

Research output: Contribution to journalArticle

Izzo, L, Frati, R, Cianfrone, F, Sassayannis, PG, Costi, U, Galati, G, Lo Mele, L, Kharrub, Z, Marini, M & Caputo, M 2004, 'Parotid Gland Cancer: A Case Report of a Primitive Adenocarcinoma Arising from a Multirecurrent Pleomorphic Adenoma', Journal of Experimental and Clinical Cancer Research, vol. 23, no. 1, pp. 153-156.
Izzo, Luciano ; Frati, R. ; Cianfrone, F. ; Sassayannis, P. G. ; Costi, U. ; Galati, G. ; Lo Mele, L. ; Kharrub, Z. ; Marini, M. ; Caputo, M. / Parotid Gland Cancer : A Case Report of a Primitive Adenocarcinoma Arising from a Multirecurrent Pleomorphic Adenoma. In: Journal of Experimental and Clinical Cancer Research. 2004 ; Vol. 23, No. 1. pp. 153-156.
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