Parotid Gland Cancer: A Case Report of a Primitive Adenocarcinoma Arising from a Multirecurrent Pleomorphic Adenoma

Luciano Izzo, R. Frati, F. Cianfrone, P. G. Sassayannis, U. Costi, G. Galati, L. Lo Mele, Z. Kharrub, M. Marini, M. Caputo

Research output: Contribution to journalArticle

Abstract

Parotid tumours represent a wide group of tumours which are mostly localized in the major salivary glands. We report a case of a 69-year old female with a parotid tumour history who was referred to us with a prominent lump and swelling localized in the right parotid area. In the period between 1985-2002, she was operated 5 times elsewhere for a recurrent pleomorphic adenoma of the right parotid (mixed tumour until 1991), which was histologically confirmed. Sixteen years after the primitive tumour, she underwent mastectomy and axillary dissection for a ductal carcinoma. Routine follow-up has been conducted on both malignancies. Pleomorphic adenoma is the most frequent tumour of the parotid. The potential risk of a malignant transformation can increase over the years with an incidence of 1% to 7%. Management of these recurrences is complex and controversial because of the different treatment options advocated such as radical resection with possible facial nerve sacrifice, or post-operative radiotherapy in non radical cases.

Original languageEnglish
Pages (from-to)153-156
Number of pages4
JournalJournal of Experimental and Clinical Cancer Research
Volume23
Issue number1
Publication statusPublished - Mar 2004

Keywords

  • Adenocarcinoma
  • Parotid cancer
  • Pleomorphic adenoma
  • Recurrent tumour

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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    Izzo, L., Frati, R., Cianfrone, F., Sassayannis, P. G., Costi, U., Galati, G., Lo Mele, L., Kharrub, Z., Marini, M., & Caputo, M. (2004). Parotid Gland Cancer: A Case Report of a Primitive Adenocarcinoma Arising from a Multirecurrent Pleomorphic Adenoma. Journal of Experimental and Clinical Cancer Research, 23(1), 153-156.