Partial irradiation of the breast: Old challenges, new solutions

J. Bernier, G. Viale, R. Orecchia, B. Ballardini, A. Richetti, L. Bronz, A. Franzetti-Pellanda, M. Intra, U. Veronesi

Research output: Contribution to journalArticlepeer-review


Breast-conserving treatment, characteristically consisting of surgical removal of the tumor and post-operative whole breast irradiation, is nowadays considered as the standard therapeutic approach for most women with stage I/II, invasive breast cancer. Recently, a number of institutions started investigating the feasibility and safety of novel approaches in radiotherapy, modulating concomitantly treatment time and irradiation volume. Whilst this strategy is still under investigation, recent clinical studies on accelerated partial breast irradiation with intra-operative radiotherapy or high conformality irradiation strongly suggest that the way patients with early breast cancer are irradiated should be revisited.

Original languageEnglish
Pages (from-to)466-475
Number of pages10
Issue number4
Publication statusPublished - Aug 2006


  • Brachytherapy
  • Breast cancer
  • Intensity-modulated radiotherapy
  • Intra-operative radiotherapy
  • Partial breast irradiation

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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