Partial volume correction of small animal PET cardiac dynamic images using iterative reconstruction: Effects on glucose metabolic rate measurement

D. D'Ambrosio, G. Fiacchi, P. Cilibrizzi, C. Lamberti, G. Baldazzi, S. Boschi, R. Franchi, M. Marengo, A. E. Spinelli

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Small animal positron emission tomography (PET) image quantitation is severely affected by partial volume effect (PVE) caused by the spatial resolution of PET tomographs. The aim of this work was to reduce the PVE using a modified iterative expectation maximization (EM) reconstruction algorithm. The goal of the method was to increase the accuracy of tracer concentration values in order to obtain an in vivo better estimate of physiological parameters. The performance of the proposed correction method was evaluated by calculating left ventricle and myocardium mean value using simulated cardiac fluorodeoxyglucose (FDG) dynamic images.

Original languageEnglish
Title of host publicationComputers in Cardiology
Pages1093-1096
Number of pages4
Volume35
DOIs
Publication statusPublished - 2008
EventComputers in Cardiology 2008, CAR - Bologna, Italy
Duration: Sep 14 2008Sep 17 2008

Other

OtherComputers in Cardiology 2008, CAR
CountryItaly
CityBologna
Period9/14/089/17/08

ASJC Scopus subject areas

  • Computer Science Applications
  • Cardiology and Cardiovascular Medicine

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