Partial volume correction of small animal PET cardiac dynamic images using iterative reconstruction: Effects on glucose metabolic rate measurement

D. D'Ambrosio; G. Fiacchi; P. Cilibrizzi; C. Lamberti; G. Baldazzi; S. Boschi; R. Franchi; M. Marengo; A. E. Spinelli

doi:10.1109/CIC.2008.4749236

Partial volume correction of small animal PET cardiac dynamic images using iterative reconstruction: Effects on glucose metabolic rate measurement

D. D'Ambrosio, G. Fiacchi, P. Cilibrizzi, C. Lamberti, G. Baldazzi, S. Boschi, R. Franchi, M. Marengo, A. E. Spinelli

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Small animal positron emission tomography (PET) image quantitation is severely affected by partial volume effect (PVE) caused by the spatial resolution of PET tomographs. The aim of this work was to reduce the PVE using a modified iterative expectation maximization (EM) reconstruction algorithm. The goal of the method was to increase the accuracy of tracer concentration values in order to obtain an in vivo better estimate of physiological parameters. The performance of the proposed correction method was evaluated by calculating left ventricle and myocardium mean value using simulated cardiac fluorodeoxyglucose (FDG) dynamic images.

Original language	English
Title of host publication	Computers in Cardiology
Pages	1093-1096
Number of pages	4
Volume	35
DOIs	https://doi.org/10.1109/CIC.2008.4749236
Publication status	Published - 2008
Event	Computers in Cardiology 2008, CAR - Bologna, Italy Duration: Sep 14 2008 → Sep 17 2008

Other

Other	Computers in Cardiology 2008, CAR
Country/Territory	Italy
City	Bologna
Period	9/14/08 → 9/17/08

ASJC Scopus subject areas

Computer Science Applications
Cardiology and Cardiovascular Medicine

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10.1109/CIC.2008.4749236

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D'Ambrosio, D., Fiacchi, G., Cilibrizzi, P., Lamberti, C., Baldazzi, G., Boschi, S., Franchi, R., Marengo, M., & Spinelli, A. E. (2008). Partial volume correction of small animal PET cardiac dynamic images using iterative reconstruction: Effects on glucose metabolic rate measurement. In Computers in Cardiology (Vol. 35, pp. 1093-1096). [4749236] https://doi.org/10.1109/CIC.2008.4749236

Partial volume correction of small animal PET cardiac dynamic images using iterative reconstruction : Effects on glucose metabolic rate measurement. / D'Ambrosio, D.; Fiacchi, G.; Cilibrizzi, P.; Lamberti, C.; Baldazzi, G.; Boschi, S.; Franchi, R.; Marengo, M.; Spinelli, A. E.

Computers in Cardiology. Vol. 35 2008. p. 1093-1096 4749236.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

D'Ambrosio, D, Fiacchi, G, Cilibrizzi, P, Lamberti, C, Baldazzi, G, Boschi, S, Franchi, R, Marengo, M & Spinelli, AE 2008, Partial volume correction of small animal PET cardiac dynamic images using iterative reconstruction: Effects on glucose metabolic rate measurement. in Computers in Cardiology. vol. 35, 4749236, pp. 1093-1096, Computers in Cardiology 2008, CAR, Bologna, Italy, 9/14/08. https://doi.org/10.1109/CIC.2008.4749236

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abstract = "Small animal positron emission tomography (PET) image quantitation is severely affected by partial volume effect (PVE) caused by the spatial resolution of PET tomographs. The aim of this work was to reduce the PVE using a modified iterative expectation maximization (EM) reconstruction algorithm. The goal of the method was to increase the accuracy of tracer concentration values in order to obtain an in vivo better estimate of physiological parameters. The performance of the proposed correction method was evaluated by calculating left ventricle and myocardium mean value using simulated cardiac fluorodeoxyglucose (FDG) dynamic images.",

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AU - Lamberti, C.

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AB - Small animal positron emission tomography (PET) image quantitation is severely affected by partial volume effect (PVE) caused by the spatial resolution of PET tomographs. The aim of this work was to reduce the PVE using a modified iterative expectation maximization (EM) reconstruction algorithm. The goal of the method was to increase the accuracy of tracer concentration values in order to obtain an in vivo better estimate of physiological parameters. The performance of the proposed correction method was evaluated by calculating left ventricle and myocardium mean value using simulated cardiac fluorodeoxyglucose (FDG) dynamic images.

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Partial volume correction of small animal PET cardiac dynamic images using iterative reconstruction: Effects on glucose metabolic rate measurement

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