Particle image velocimetry analysis of the flow field in the total cavopulmonary connection

M. Grigioni, A. Amodeo, C. Daniele, G. D'Avenio, R. Formigari, R. M. Di Donato

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The total cavopulmonary connection (TCPC) is a common operation, meant to restore a proper pulmonary blood flow in heart defects with only one functional ventricle. It consists of the direct connection of the venae cavae to the pulmonary arteries in a cross-shaped disposition which entails a peculiar hemodynamics: Side effects can occur, such as recirculation zones and pressure drop across the connection. Our study is aimed at the quantitative investigation of the flow field of a successful Fontan-type operation, in view of the clinical importance of assuring a nearly physiological pulmonary blood flow. especially if one considers that many pediatric patients are eligible for this operation. A glass-blown TCPC phantom, realized according to nuclear magnetic resonance data, was employed in a steady-flow loop. Thus, a realistic model of this Fontan-type operation was realized using materials which enable advanced measurement techniques such as particle image velocimetry (PIV). The mean flow tales at each branch or the cavopulmonary shunt could be independently varied with a vertical shift of the corresponding upstream reservoir. The PIV technique was used successfully in identifying the flow field characteristics. The flow field in this TCPC topology was shown to be well organized and regulated by the presence of a vortex at the confluence of the venae cavae. The effect of different loading conditions, which realistically can be found in vivo, is studied with a high spatial resolution, showing the possibility to use pulmonary resistance as a parameter in designing the surgical geometry.

Original languageEnglish
Pages (from-to)946-952
Number of pages7
JournalArtificial Organs
Volume24
Issue number12
DOIs
Publication statusPublished - 2000

Fingerprint

Rheology
Velocity measurement
Fontan Procedure
Flow fields
Venae Cavae
Lung
Blood
Right Heart Bypass
Pediatrics
Hemodynamics
Steady flow
Pulmonary Artery
Pressure drop
Glass
Vortex flow
Magnetic Resonance Spectroscopy
Nuclear magnetic resonance
Topology
Pressure
Defects

Keywords

  • Biological flows
  • Fontan-type circulation
  • In vitro testing
  • Particle image velocimetry
  • Pulmonary flow
  • Total cavopulmonary connection

ASJC Scopus subject areas

  • Biophysics

Cite this

Particle image velocimetry analysis of the flow field in the total cavopulmonary connection. / Grigioni, M.; Amodeo, A.; Daniele, C.; D'Avenio, G.; Formigari, R.; Di Donato, R. M.

In: Artificial Organs, Vol. 24, No. 12, 2000, p. 946-952.

Research output: Contribution to journalArticle

Grigioni, M. ; Amodeo, A. ; Daniele, C. ; D'Avenio, G. ; Formigari, R. ; Di Donato, R. M. / Particle image velocimetry analysis of the flow field in the total cavopulmonary connection. In: Artificial Organs. 2000 ; Vol. 24, No. 12. pp. 946-952.
@article{c8966d74a18e4521975d9d6a38e13dd0,
title = "Particle image velocimetry analysis of the flow field in the total cavopulmonary connection",
abstract = "The total cavopulmonary connection (TCPC) is a common operation, meant to restore a proper pulmonary blood flow in heart defects with only one functional ventricle. It consists of the direct connection of the venae cavae to the pulmonary arteries in a cross-shaped disposition which entails a peculiar hemodynamics: Side effects can occur, such as recirculation zones and pressure drop across the connection. Our study is aimed at the quantitative investigation of the flow field of a successful Fontan-type operation, in view of the clinical importance of assuring a nearly physiological pulmonary blood flow. especially if one considers that many pediatric patients are eligible for this operation. A glass-blown TCPC phantom, realized according to nuclear magnetic resonance data, was employed in a steady-flow loop. Thus, a realistic model of this Fontan-type operation was realized using materials which enable advanced measurement techniques such as particle image velocimetry (PIV). The mean flow tales at each branch or the cavopulmonary shunt could be independently varied with a vertical shift of the corresponding upstream reservoir. The PIV technique was used successfully in identifying the flow field characteristics. The flow field in this TCPC topology was shown to be well organized and regulated by the presence of a vortex at the confluence of the venae cavae. The effect of different loading conditions, which realistically can be found in vivo, is studied with a high spatial resolution, showing the possibility to use pulmonary resistance as a parameter in designing the surgical geometry.",
keywords = "Biological flows, Fontan-type circulation, In vitro testing, Particle image velocimetry, Pulmonary flow, Total cavopulmonary connection",
author = "M. Grigioni and A. Amodeo and C. Daniele and G. D'Avenio and R. Formigari and {Di Donato}, {R. M.}",
year = "2000",
doi = "10.1046/j.1525-1594.2000.06613.x",
language = "English",
volume = "24",
pages = "946--952",
journal = "Artificial Organs",
issn = "0160-564X",
publisher = "Wiley-Blackwell",
number = "12",

}

TY - JOUR

T1 - Particle image velocimetry analysis of the flow field in the total cavopulmonary connection

AU - Grigioni, M.

AU - Amodeo, A.

AU - Daniele, C.

AU - D'Avenio, G.

AU - Formigari, R.

AU - Di Donato, R. M.

PY - 2000

Y1 - 2000

N2 - The total cavopulmonary connection (TCPC) is a common operation, meant to restore a proper pulmonary blood flow in heart defects with only one functional ventricle. It consists of the direct connection of the venae cavae to the pulmonary arteries in a cross-shaped disposition which entails a peculiar hemodynamics: Side effects can occur, such as recirculation zones and pressure drop across the connection. Our study is aimed at the quantitative investigation of the flow field of a successful Fontan-type operation, in view of the clinical importance of assuring a nearly physiological pulmonary blood flow. especially if one considers that many pediatric patients are eligible for this operation. A glass-blown TCPC phantom, realized according to nuclear magnetic resonance data, was employed in a steady-flow loop. Thus, a realistic model of this Fontan-type operation was realized using materials which enable advanced measurement techniques such as particle image velocimetry (PIV). The mean flow tales at each branch or the cavopulmonary shunt could be independently varied with a vertical shift of the corresponding upstream reservoir. The PIV technique was used successfully in identifying the flow field characteristics. The flow field in this TCPC topology was shown to be well organized and regulated by the presence of a vortex at the confluence of the venae cavae. The effect of different loading conditions, which realistically can be found in vivo, is studied with a high spatial resolution, showing the possibility to use pulmonary resistance as a parameter in designing the surgical geometry.

AB - The total cavopulmonary connection (TCPC) is a common operation, meant to restore a proper pulmonary blood flow in heart defects with only one functional ventricle. It consists of the direct connection of the venae cavae to the pulmonary arteries in a cross-shaped disposition which entails a peculiar hemodynamics: Side effects can occur, such as recirculation zones and pressure drop across the connection. Our study is aimed at the quantitative investigation of the flow field of a successful Fontan-type operation, in view of the clinical importance of assuring a nearly physiological pulmonary blood flow. especially if one considers that many pediatric patients are eligible for this operation. A glass-blown TCPC phantom, realized according to nuclear magnetic resonance data, was employed in a steady-flow loop. Thus, a realistic model of this Fontan-type operation was realized using materials which enable advanced measurement techniques such as particle image velocimetry (PIV). The mean flow tales at each branch or the cavopulmonary shunt could be independently varied with a vertical shift of the corresponding upstream reservoir. The PIV technique was used successfully in identifying the flow field characteristics. The flow field in this TCPC topology was shown to be well organized and regulated by the presence of a vortex at the confluence of the venae cavae. The effect of different loading conditions, which realistically can be found in vivo, is studied with a high spatial resolution, showing the possibility to use pulmonary resistance as a parameter in designing the surgical geometry.

KW - Biological flows

KW - Fontan-type circulation

KW - In vitro testing

KW - Particle image velocimetry

KW - Pulmonary flow

KW - Total cavopulmonary connection

UR - http://www.scopus.com/inward/record.url?scp=0034512866&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034512866&partnerID=8YFLogxK

U2 - 10.1046/j.1525-1594.2000.06613.x

DO - 10.1046/j.1525-1594.2000.06613.x

M3 - Article

C2 - 11121974

AN - SCOPUS:0034512866

VL - 24

SP - 946

EP - 952

JO - Artificial Organs

JF - Artificial Organs

SN - 0160-564X

IS - 12

ER -